Self-Assembling Ligands for Multivalent Nanoscale Heparin Binding

被引：68

作者：

Rodrigo, Ana C. ^{[1
]}

Barnard, Anna ^{[1
]}

Cooper, James ^{[1
]}

Smith, David K. ^{[1
]}

机构：

[1] Univ York, Dept Chem, York YO10 5DD, N Yorkshire, England

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2011年 / 50卷 / 20期

基金：

英国生物技术与生命科学研究理事会;

关键词：

heparin; ligands; nanostructures; self-assembly; supramolecular chemistry; MOLECULAR-WEIGHT; DNA-BINDING; GENE DELIVERY; DENDRIMERS; DENDRONS; SULFATE; SURFACE; DESIGN; RECOGNITION; RECEPTORS;

D O I：

10.1002/anie.201100019

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Supramolecular string of pearls: Polycationic ligands are designed to self-assemble into spherical pseudo-dendrimers that are capable of binding polyanionic heparin with affinities and binding modes similar to covalent nanostructures such as dendrimers and proteins (see picture; purple: heparin, red/blue: self-assembling ligand). Binding of the ligands to heparin induces nanoscale organization of the formed nanostructures. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：4675 / 4679

页数：5

共 50 条

[21] Pyrene-Based Self-Assembling Peptide for Ratiometric Detection of Heparin
Shao, Liang
Yu, Hongwen
Song, Jiaqi
Liu, Shichang
Li, Guanying
CHEMBIOCHEM, 2023, 24 (05)
[22] Delivering Heparin-Binding Insulin-Like Growth Factor 1 with Self-Assembling Peptide Hydrogels
Florine, Emily M.
Miller, Rachel E.
Liebesny, Paul H.
Mroszczyk, Keri A.
Lee, Richard T.
Patwari, Parth
Grodzinsky, Alan J.
TISSUE ENGINEERING PART A, 2015, 21 (3-4) : 637 - 646
[23] Enhanced Antibacterial Properties of Self-Assembling Peptide Amphiphiles Functionalized with Heparin-Binding Cardin-Motifs
Chang, Run
Subramanian, Keerthana
Wang, Mian
Webster, Thomas J.
ACS APPLIED MATERIALS & INTERFACES, 2017, 9 (27) : 22350 - 22360
[24] Self-assembling Trees
Danos, Vincent
Krivine, Jean
Tarissan, Fabien
ELECTRONIC NOTES IN THEORETICAL COMPUTER SCIENCE, 2007, 175 (01) : 19 - 32
[25] SELF-ASSEMBLING MATERIALS
WHITESIDES, GM
SCIENTIFIC AMERICAN, 1995, 273 (03) : 146 - 149
[26] SELF-ASSEMBLING CYTOTOXINS
RIDEOUT, D
SCIENCE, 1986, 233 (4763) : 561 - 563
[27] Self-assembling Games
Barrett, Jeffrey A.
Skyrms, Brian
BRITISH JOURNAL FOR THE PHILOSOPHY OF SCIENCE, 2017, 68 (02): : 329 - 353
[28] Self-assembling prodrugs
Cheetham, Andrew G.
Chakroun, Rami W.
Ma, Wang
Cui, Honggang
CHEMICAL SOCIETY REVIEWS, 2017, 46 (21) : 6638 - 6663
[29] Self-assembling capsules
Conn, MM
Rebek, J
CHEMICAL REVIEWS, 1997, 97 (05) : 1647 - 1668
[30] Self-assembling life
不详
NATURE NANOTECHNOLOGY, 2016, 11 (11) : 909 - 909

← 1 2 3 4 5 →