ANTI-CANCER DOCKING INVESTIGATIONS, ANTI-OXIDANT PROPERTIES AND MICROWAVE-ASSISTED SYNTHESIS OF 1-(4-((2-((7-HYDROXY-1, 8-NAPHTHYRIDIN-2-YL) AMINO)-6- PHENYLPYRIMIDIN-4-YL) AMINO)PHENYL)-3-ARYLPROP-2-EN-1-ONES

被引：0
|
作者：
Reddy, B. Srinivasa [1 ]
Rajeshwari, M. [2 ]
Bhaskar, P. [3 ]
Ramesh, D. [4 ]
Laxminarayana, E. [5 ]
机构：
[1] Mahatma Gandhi Inst Technol, Hyderabad 500075, Telangana, India
[2] Telangana Univ, Nizamabad 503322, Telagana, India
[3] Nalla Narasimha Reddy Educ Societys Grp Inst Inte, Korremula XRd, Hyderabad 500088, India
[4] Mahatma Gandhi Univ, Dept Chem & Pharmaceut Sci, Nalgonda 508544, India
[5] Sreenidhi Inst Sci & Technol Autonomous, Hyderabad 501301, Telangana, India
来源：
HETEROCYCLIC LETTERS | 2021年 / 11卷 / 04期
关键词：
Microwave; Chalcones; Pyrimidine; 1; 8-Naphthyridine anti-oxidant activity; SOLVENT-FREE; ANTIINFLAMMATORY ACTIVITY; HYBRIDS SYNTHESIS; IRRADIATION; FACILE; DESIGN;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
This study discuss a reliable, convenient an energy-efficient and environmentally benign synthesis of 2-substituted 1,8-Naphthyridine derivatives under microwave synthesis with excellent yields. This is atom economical method, presented in this communication. The advantages of this protocol are green, clean and efficient, less reaction time, easy workup and high yields, further the compounds tested for antioxidant activity, the compounds 5b, 5c, 5d exhibited significant activity.
引用
收藏
页码：627 / 637
页数：11
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