Enhancement of magnetic particle production by nitrate and succinate fed-batch culture of Magnetospirillum sp Amb-1

被引：0

作者：

Matsunaga, T ^{[1
]}

Tsujimura, N ^{[1
]}

Kamiya, S ^{[1
]}

机构：

[1] TDK CO,CTR RES & DEV,ICHIKAWA,CHIBA 272,JAPAN

来源：

BIOTECHNOLOGY TECHNIQUES | 1996年 / 10卷 / 07期

关键词：

D O I：

暂无

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Magnetospirillum sp. AMB-1 is a magnetic bacterium, which is capable of growing under air atmosphere. This bacterium was employed to make bacterial magnetic particles (BMPs). AMB-1 only makes BMPs during logarithmic growth phase under anaerobic conditions. Since it requires nitrate as a nitrogen source, control of nitrate concentration in the medium was necessary. The fed-batch culture of AMB-1 was carried out by adding nitric acid and succinate as nitrogen and carbon source respectively. One liter of AMB-1 culture produced 0.34 g of dry cells and 4.5 mg of BMPs. BMP production by AMB-1 cultivated in the fed-batch culture was found to be seven times higher than that cultivated in the batch culture.

引用

页码：495 / 500

页数：6

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