Contribution of the addition of anti-ββ2-glycoprotein to the classification of antiphospholipid syndrome in predicting adverse pregnancy outcome

Methods. aEuro integral A retrospective cohort design was used. Ninety-one patients (total 394 pregnancies) referred to a tertiary medical center for evaluation of clinical features consistent with APS were divided into three groups: group A (n == 34), two positive tests for anticardiolipin (ACL) or lupus anticoagulant (LAC), in accordance with original APS classification (1998); group B (n == 18), two positive tests for a-beta beta 2GP1, in accordance with the revised APS criteria; and group C (n == 39), only one positive test for ACL or LAC. Results. aEuro integral Of the 52 women with APS (group A or B), 36 had primary disease, and 16 had secondary disease. On comparison of the groups, group B was characterized by a significantly higher rate of complicated pregnancy (83.3%%) than groups A (47.1%%) and C (76.9%%), P == 0.007, and a higher rate of fetal loss (72.2%%) than groups A ++ C (28.8%%, P == 0.001). Conclusions. aEuro integral The findings suggest that the revised APS criteria are preferable to the original classification for the prediction of complicated pregnancy.