Effect of mercuric chloride on circulating hormones in adult albino rats

被引:0
|
作者
Ramalingam, V [1 ]
Vimaladevi, V
Rajeswary, S
Suryavathi, V
机构
[1] Bharathidasan Govt Coll Women, Dept Zool, Pondicherry 605003, India
[2] KM Ctr PG Studies, Dept Zool, Pondicherry 605008, India
来源
JOURNAL OF ENVIRONMENTAL BIOLOGY | 2003年 / 24卷 / 04期
关键词
mercuric chloride; rat; testosterone; LH; FSH; prolactin;
D O I
暂无
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
The effect of mercuric chloride at two different doses, 0.5 mg/kg body weight (low dose), 1 mg/kg body weight (high dose), for 30 days, was seen on the circulating hormones in the mature male albino rats. Testosterone level was markedly decreased in the low dose (P< 0.01) and high dose (P< 0.001) treated animals. The level of luteinizing hormone (LH) was also reduced in the low dose (P< 0.01) as well as in the high dose (P< 0.001) treated animals. However, follicle stimulating hormone (FSH) and prolactin (FRL) levels were found to be decreased only in the high dose (P< 0.05) treated animals and no change was observed in the low dose treated animals. The changes in the hormone levels caused by the mercuric chloride treatment suggest the dysfunction of pituitary-testicular axis.
引用
收藏
页码:401 / 404
页数:4
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