TOWARDS ON-CHIP CHEMICAL REACTION MONITORING BY EWOD IMPEDANCE MEASUREMENT

被引：0
|
作者：
Ma, Xiaoxiao [1 ,2 ]
Chen, Supin [3 ]
Kim, Chang-Jin CJ [3 ,4 ]
van Dam, R. Michael [1 ,2 ,3 ]
机构：
[1] Univ Calif Los Angeles, Dept Mol & Med Pharmacol, Los Angeles, CA 90095 USA
[2] Univ Calif Los Angeles, Crump Inst Mol Imaging, Los Angeles, CA 90095 USA
[3] Univ Calif Los Angeles, Bioengn Dept, Los Angeles, CA 90095 USA
[4] Univ Calif Los Angeles, Mech & Aerosp Engn Dept, Los Angeles, CA 90095 USA
来源：
2014 IEEE 27TH INTERNATIONAL CONFERENCE ON MICRO ELECTRO MECHANICAL SYSTEMS (MEMS) | 2014年
关键词：
DIGITAL MICROFLUIDICS;
D O I：
暂无
中图分类号：
TM [电工技术]; TN [电子技术、通信技术];
学科分类号：
0808 ; 0809 ;
摘要：
This paper demonstrates the use of impedance sensing in an electrowetting-on-dielectric (EWOD) chip to monitor the progress of a chemical reaction. Sensing is achieved by measuring the current through a sample droplet with the aid of a lock-in amplifier. Monitoring of the reaction of HCl with NaOH (i.e., during a titration) was demonstrated. A sharp minimum in the impedance signal was observed at the titration equivalence point, enabling the endpoint to be determined electronically. Future work is aimed at extending reaction monitoring to additional acid-base systems and other classes of reactions.
引用
收藏
页码：338 / 341
页数：4
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