Enantioselective hydride abstraction in organic substrate: A novel use for chiral carbenium ions

被引：23

作者：

Magdziak, D ^{[1
]}

Pettus, LPH ^{[1
]}

Pettus, TRR ^{[1
]}

机构：

[1] Univ Calif Santa Barbara, Dept Chem & Biochem, Santa Barbara, CA 93106 USA

来源：

ORGANIC LETTERS | 2001年 / 3卷 / 04期

关键词：

D O I：

10.1021/ol006963k

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] It is surprising that chiral cations have not been used to distinguish between prochiral hydrides when converse notions, such as asymmetric addition of a hyride to a prochiral functional group or use of a chiral anion to distinghish between a pair of prochiral protons, are methods employed everyday in enantioselective synthesis. To the best of our knowledge, this Letter describes the first example ol an oxidative enantioselective hydride transfer process.

引用

页码：557 / 559

页数：3