Notch Signaling: Where Is the Action?

被引:0
|
作者
Januschke, Jens [1 ]
Wodarz, Andreas [2 ,3 ]
机构
[1] Univ Dundee, Sch Life Sci, Cell & Dev Biol, JBC WBT MSI Complex, Dundee DD1 5EH, Scotland
[2] Univ Cologne, Med Sch, Inst Anat 1, Mol Cell Biol, Kerpener Str 62, D-50937 Cologne, Germany
[3] Cellular Stress Response Aging Associated Dis CEC, Cluster Excellence, Joseph Stelzmann Str 26, D-50931 Cologne, Germany
关键词
ASYMMETRIC CELL-DIVISION; SARA ENDOSOMES; TRAFFICKING;
D O I
10.1016/j.cub.2017.06.072
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
It has been a long-standing question as to whether the activation of Notch by its ligands occurs in a specific region of the plasma membrane. A study now shows that this is indeed the case in the Drosophila sensory organ precursor cell lineage.
引用
收藏
页码:R760 / R762
页数:4
相关论文
共 50 条
  • [11] Notch signaling
    Miele, L
    CLINICAL CANCER RESEARCH, 2006, 12 (04) : 1074 - 1079
  • [12] Notch signaling
    Hess, Sandra
    Pfreundschuh, Michael
    Gleissner, Beate
    JOURNAL OF NEUROSURGERY, 2007, 107 (05) : 1060 - 1061
  • [13] NOTCH SIGNALING
    ARTAVANISTSAKONAS, S
    MATSUNO, K
    FORTINI, ME
    SCIENCE, 1995, 268 (5208) : 225 - 232
  • [14] Notch Signaling
    Kopan, Raphael
    COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY, 2012, 4 (10):
  • [15] Notch Signaling in Embryology and Cancer Notch Signaling in Embryology Preface
    Reichrath, Joerg
    Reichrath, Sandra
    NOTCH SIGNALING IN EMBRYOLOGY AND CANCER: NOTCH SIGNALING IN EMBRYOLOGY, 2020, 1218 : VII - VIII
  • [16] Notch Signaling in Embryology and Cancer Notch Signaling in Cancer Preface
    Reichrath, Sandra
    Reichrath, Joerg
    NOTCH SIGNALING IN EMBRYOLOGY AND CANCER: NOTCH SIGNALING IN CANCER, 2020, 1287 : VII - X
  • [17] Notch signaling in neuroblastoma
    Påhlman, S
    Stockhausen, MT
    Fredlund, E
    Axelson, H
    SEMINARS IN CANCER BIOLOGY, 2004, 14 (05) : 365 - 373
  • [18] Notch signaling in somitogenesis
    Mara, A.
    Schroeder, J.
    Chaloun, C.
    Holley, S. A.
    BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY, 2007, 79 (05) : 389 - 389
  • [19] Top NOTCH Targets: Notch Signaling in Cancer
    Jun, H. Toni
    Stevens, Jennitte
    Kaplan-Lefko, Paula
    DRUG DEVELOPMENT RESEARCH, 2008, 69 (06) : 319 - 328
  • [20] Notch signaling is bone
    LEe, B.
    CALCIFIED TISSUE INTERNATIONAL, 2008, 82 : S16 - S16