This paper describes the R package cold for the analysis of count longitudinal data. In this package marginal and random effects models are considered. In both cases estimation is via maximization of the exact likelihood and serial dependence among observations is assumed to be of Markovian type and referred as the integer-valued autoregressive of order one process. For random effects models adaptive Gaussian quadrature and Monte Carlo methods are used to compute integrals whose dimension depends on the structure of random effects. cold is written partly in R language, partly in Fortran 77, interfaced through R and is built following the S4 formulation of R methods.
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UT MD Anderson Canc Ctr, Dept Bioinformat & Computat Biol, Houston, TX 77030 USAUT MD Anderson Canc Ctr, Dept Bioinformat & Computat Biol, Houston, TX 77030 USA
Zhang, Nianxiang
Xu, Yan
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Stanford Univ, Stanford Genome Technol Ctr, Palo Alto, CA 94304 USAUT MD Anderson Canc Ctr, Dept Bioinformat & Computat Biol, Houston, TX 77030 USA
Xu, Yan
O'Hely, Martin
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Walter & Eliza Hall Inst Med Res, Bioinformat Div, Parkville, Vic 3052, AustraliaUT MD Anderson Canc Ctr, Dept Bioinformat & Computat Biol, Houston, TX 77030 USA
O'Hely, Martin
Speed, Terence P.
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Walter & Eliza Hall Inst Med Res, Bioinformat Div, Parkville, Vic 3052, Australia
Univ Calif Berkeley, Dept Stat, Berkeley, CA 94720 USAUT MD Anderson Canc Ctr, Dept Bioinformat & Computat Biol, Houston, TX 77030 USA
Speed, Terence P.
Scharfe, Curt
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Stanford Univ, Stanford Genome Technol Ctr, Palo Alto, CA 94304 USAUT MD Anderson Canc Ctr, Dept Bioinformat & Computat Biol, Houston, TX 77030 USA
Scharfe, Curt
Wang, Wenyi
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UT MD Anderson Canc Ctr, Dept Bioinformat & Computat Biol, Houston, TX 77030 USAUT MD Anderson Canc Ctr, Dept Bioinformat & Computat Biol, Houston, TX 77030 USA