A julolidine-fused coumarin-NBD dyad for highly selective and sensitive detection of H2S in biological samples

被引：33
|
作者：
Ismail, Ismail [1 ]
Wang, Dawei [1 ]
Wang, Zhenghua [1 ]
Wang, Dan [1 ]
Zhang, Changyu [2 ]
Yi, Long [2 ,3 ]
Xi, Zhen [1 ,3 ]
机构：
[1] Nankai Univ, State Key Lab Elementoorgan Chem, Natl Pesticide Engn Res Ctr, Dept Chem Biol,Coll Chem, Tianjin 300071, Peoples R China
[2] Beijing Univ Chem Technol, Beijing Key Lab Bioproc, 15 Beisanhuan East Rd, Beijing 100029, Peoples R China
[3] Nankai Univ, Collaborat Innovat Ctr Chem Sci & Engn, Tianjin, Peoples R China
来源：
DYES AND PIGMENTS | 2019年 / 163卷
基金：
国家重点研发计划;
关键词：
Julolidine-fused coumarin-NBD probe; H2S detection; Cell imaging; Zebrafish imaging; RATIOMETRIC FLUORESCENT-PROBE; TURN-ON PROBE; HYDROGEN-SULFIDE; RAPID DETECTION; LIVING CELLS; CYSTEINE; THIOLYSIS; CANCER; AUTOPHAGY; SYNTHASE;
D O I：
10.1016/j.dyepig.2018.12.064
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
A new julolidine-fused coumarin-NBD probe 2 for H2S detection is rationally designed based on the DFT culations. This improved probe exhibits faster and larger off-on response as well as higher sensitivity compare with the previous coumarin-NBD probe 1. Moreover, 2 possesses excellent selectivity and good biocompatibility which can be employed to image H2S in living cells and in zebrafish.
引用
收藏
页码：700 / 706
页数：7
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