A fluoro analogue of UDP-α-D-glucuronic acid is an inhibitor of UDP-α-D-apiose/UDP-α-D-xylose synthase

被引：12
|
作者：
Choi, Sei-hyun [1 ]
Ruszczycky, Mark W. [2 ]
Zhang, Hua [2 ]
Liu, Hung-wen [1 ,2 ]
机构：
[1] Univ Texas Austin, Dept Chem & Biochem, Austin, TX 78712 USA
[2] Univ Texas Austin, Coll Pharm, Div Med Chem, Austin, TX 78712 USA
来源：
CHEMICAL COMMUNICATIONS | 2011年 / 47卷 / 36期
基金：
美国国家卫生研究院;
关键词：
D-TYVELOSE; 2-EPIMERASE; LEMNA-MINOR; CELL-WALL; GALACTOSE; 4-EPIMERASE; RHAMNOGALACTURONAN-II; ESCHERICHIA-COLI; MOLECULAR-STRUCTURE; BIOSYNTHESIS; APIOGALACTURONAN; POLYSACCHARIDE;
D O I：
10.1039/c1cc13140k
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
UDP-2F-glucuronic acid was synthesized and analyzed as a mechanistic probe to investigate the ring contraction step catalyzed by UDP-D-apiose/UDP-D-xylose synthase (AXS).
引用
收藏
页码：10130 / 10132
页数：3
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