Synthesis and evaluation of Schiff bases and 4-thiazolidinones as antibacterial agents

被引：0
|
作者：
Solankee, Anjani N. [1 ]
机构：
[1] BKM Sci Coll, Dept Chem, Valsad 396001, Gujarat, India
来源：
JOURNAL OF THE INDIAN CHEMICAL SOCIETY | 2011年 / 88卷 / 11期
关键词：
Schiff bases; 4-thiazolidinones; thioglycolic acid; antibacterial activity; MANNICH REACTION-PRODUCTS; ANTIFUNGAL ACTIVITY; BIOLOGICAL-ACTIVITY; FUNGITOXICITY;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
6-Methylpyridine-3-carbohydrazide (2) on condensation with different aromatic aldehydes (1) resulted in Schiff bases 3(a-i), which on cyclocondensation with thioglycolic acid resulted in 4-thiazolidinones 4(a-i). The newly synthesized compounds were characterized using IR, H-1 NMR, C-13 NMR and elemental analysis. Synthesized compounds were evaluated for their in vitro antibacterial activity against Gram-positive and Gram-negative strains.
引用
收藏
页码：1733 / 1738
页数：6
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