A Guide to COVID-19: a global pandemic caused by the novel coronavirus SARS-CoV-2

被引:174
|
作者
Atzrodt, Cassandra L. [1 ]
Maknojia, Insha [1 ]
McCarthy, Robert D. P. [1 ]
Oldfield, Tiara M. [1 ]
Po, Jonathan [1 ]
Ta, Kenny T. L. [1 ]
Stepp, Hannah E. [1 ]
Clements, Thomas P. [1 ]
机构
[1] Vanderbilt Univ, Dept Biol Sci, 1210 Biol Sci MRB,465 21st St South, Nashville, TN 37235 USA
关键词
ACE2; coronavirus; COVID-19; CRISPR; MERS; MERS-CoV; SARS; SARS-CoV; SARS-CoV-2; vaccine; SPIKE PROTEIN; SARS-COV; 2019-NCOV; PATHOGENESIS; PCR; EPIDEMIOLOGY; TRANSMISSION; MECHANISMS; INHIBITION; MANAGEMENT;
D O I
10.1111/febs.15375
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The emergence of the SARS-CoV-2 strain of the human coronavirus has thrown the world into the midst of a new pandemic. In the human body, the virus causes COVID-19, a disease characterized by shortness of breath, fever, and pneumonia, which can be fatal in vulnerable individuals. SARS-CoV-2 has characteristics of past human coronaviruses, with close genomic similarities to SARS-CoV, the virus that causes the disease SARS. Like these related coronaviruses, SARS-CoV-2 is transmitted through the inhalation of droplets and interaction with contaminated surfaces. Across the world, laboratories are developing candidate vaccines for the virus - with vaccine trials underway in the United States and the United Kingdom - and considering various drugs for possible treatments and prophylaxis. Here, we provide an overview of SARS-CoV-2 by analyzing its virology, epidemiology, and modes of transmission while examining the current progress of testing procedures and possible treatments through drugs and vaccines.
引用
收藏
页码:3633 / 3650
页数:18
相关论文
共 50 条
  • [41] Fake images of the SARS-CoV-2 coronavirus in the communication of information at the beginning of the first Covid-19 pandemic
    Andreu-Sanchez, Celia
    Martin-Pascual, Miguel-Angel
    PROFESIONAL DE LA INFORMACION, 2020, 29 (03): : 1 - 10
  • [42] Update of the recommendations on the management of the SARS-CoV-2 coronavirus pandemic (COVID-19) in kidney transplant patients
    Mazuecos, Auxiliadora
    Villanego, Florentino
    Alonso, Angel
    Beneyto, Isabel
    Crespo, Marta
    Diaz-Corte, Carmen
    Franco, Antonio
    Gonzalez-Roncero, Francisco
    Guirado, Luis
    Jimenez, Carlos
    Juega, Javier
    Llorente, Santiago
    Paul, Javier
    Rodriguez-Benot, Alberto
    Ruiz, Juan Carlos
    Sanchez-Fructuoso, Ana
    Torregrosa, Vicente
    Rodrigo, Emilio
    Hernandez, Domingo
    Lopez, Veronica
    Lopez-Oliva, Maria
    Zarraga, Sofia
    NEFROLOGIA, 2023, 43 (05): : 531 - 545
  • [43] Epidemiology of Coronavirus Disease 2019 (COVID-19) Caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
    Wei, Maoti
    Yang, Ning
    Wang, Fenghua
    Zhao, Guoping
    Gao, Hongwei
    Li, Yuming
    DISASTER MEDICINE AND PUBLIC HEALTH PREPAREDNESS, 2020, 14 (06) : 796 - 804
  • [44] Digital disruption and global businesses' viability under COVID-19 (SARS-CoV-2) pandemic
    Nyagadza, Brighton
    JOURNAL OF DIGITAL MEDIA & POLICY, 2023, 14 (01) : 83 - 101
  • [45] SARS-CoV-2 and Microbiological Diagnostic Dynamics in COVID-19 Pandemic
    Erensoy, Selda
    MIKROBIYOLOJI BULTENI, 2020, 54 (03): : 497 - 509
  • [46] Molecular Evolution of SARS-CoV-2 during the COVID-19 Pandemic
    Gonzalez-Vazquez, Luis Daniel
    Arenas, Miguel
    GENES, 2023, 14 (02)
  • [47] The Economic Impact of the SARS-COV-2 (COVID-19) Pandemic in Spain
    Pinilla, Jaime
    Barber, Patricia
    Vallejo-Torres, Laura
    Rodriguez-Mireles, Silvia
    Lopez-Valcarcel, Beatriz G.
    Serra-Majem, Luis
    INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 2021, 18 (09)
  • [48] Consequences of the COVID-19/SARS-CoV-2 pandemic for gastroenterology in Germany
    Frieling, Thomas
    GASTROENTEROLOGE, 2020, 15 (06): : 498 - 505
  • [49] Ratcheting down the virulence of SARS-CoV-2 in the COVID-19 pandemic
    Brufsky, Adam
    Lotze, Michael T.
    JOURNAL OF MEDICAL VIROLOGY, 2020, 92 (11) : 2379 - 2380
  • [50] COVID-19 pandemic crisis—a complete outline of SARS-CoV-2
    Sana Saffiruddin Shaikh
    Anooja P. Jose
    Disha Anil Nerkar
    Midhuna Vijaykumar KV
    Saquib Khaleel Shaikh
    Future Journal of Pharmaceutical Sciences, 6