Anti-inflammatory effects of flavonoids evaluated in murine models: a descriptive review

Several chronic diseases are directly related to inflammatory states and lead to tissue damage and failure. Millions of people die worldwide from inflammation-associated pathologies such as cardiovascular diseases, diabetes and obesity. Inadequate dietary habits contribute to a deterioration of these diseases. Diet anti-inflammatory models should be studied in more detail. Fruit and vegetable polyphenols have shown anti-inflammatory benefits. This article is aimed at evaluating the inflammatory response in different murine models administered polyphenol rich diets, with a primary focus on flavonoids extracted from plants and evaluated in several inflammatory induced conditions. Carrageenan as an inflammatory agent was used to induce inflammation and several anti-inflammatory polyphenols were monitored.