Dibutyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate, diisobutyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate and di-tert-butyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

被引：20
|
作者：
Rowan, KR
Holt, EM
机构：
[1] Department of Chemistry, Oklahoma State University, Stillwater
来源：
ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY | 1996年 / 52卷
关键词：
D O I：
10.1107/S0108270196003551
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The structures of dibutyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate, C23H30N2O6, diisobutyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate, C23H30N2O6, and di-tert-butyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate, C23H30N2O6, members of the 1,4-dihydropyridine class of calcium antagonists, have been determined. Increasing the bulk of the esterification groups, as quantified in a cone-angle analysis, leads to greater perpendicularity of the dual ring system. This leads to conclusions about the potential activity of these compounds.
引用
收藏
页码：2207 / 2212
页数：6
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