BREAST CANCER The 21-gene recurrence score - biology remains at the forefront

被引：3
|
作者：
Puhalla, Shannon L. [1 ]
Davidson, Nancy E. [1 ]
机构：
[1] Univ Pittsburgh, Inst Canc, Dept Med, 5150 Ctr Ave, Pittsburgh, PA 15232 USA
来源：
NATURE REVIEWS CLINICAL ONCOLOGY | 2016年 / 13卷 / 08期
关键词：
DISTANT RECURRENCE; EXPRESSION; THERAPY; WOMEN; RISK;
D O I：
10.1038/nrclinonc.2016.98
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
The 21-gene recurrence score is a genetic assay developed to estimate the likelihood of distant recurrence in patients with oestrogen-receptor-positive, lymph-node-negative breast cancer treated with adjuvant endocrine therapy. Now, two studies explore how the 21-gene recurrence score has been used to inform treatment decisions in this setting and beyond.
引用
收藏
页码：470 / 472
页数：2
相关论文
共 50 条
  • [41] The 21-gene recurrence score in early non-ductal breast cancer: A national cancer database analysis
    Makower, Della
    Qin, Jiyue
    Lin, Juan
    Xue, Xiaonan
    Sparano, Joseph A.
    CANCER RESEARCH, 2021, 81 (04)
  • [42] 21-Gene Recurrence Score and Adjuvant Chemotherapy Decision for Breast Cancer Patients with Positive Lymph Nodes
    Tong, Yiwei
    Wu, Jiayi
    Huang, Ou
    He, Jianrong
    Zhu, Li
    Chen, Weiguo
    Li, Yafen
    Chen, Xiaosong
    Shen, Kunwei
    SCIENTIFIC REPORTS, 2019, 9 (1)
  • [43] Economic impact of 21-gene recurrence score testing on early-stage breast cancer in Ireland
    Smyth, Lillian
    Watson, Geoff
    Walsh, Elaine M.
    Kelly, Catherine M.
    Keane, Maccon
    Kennedy, M. John
    Grogan, Liam
    Hennessy, Bryan T.
    O'Reilly, Seamus
    Coate, Linda E.
    O'Connor, Miriam
    Quinn, Cecily
    Verleger, Katharina
    Schoeman, Olaf
    O'Reilly, Susan
    Walshe, Janice M.
    BREAST CANCER RESEARCH AND TREATMENT, 2015, 153 (03) : 573 - 582
  • [44] Association between standard clinical and pathologic characteristics and the 21-gene recurrence score in breast cancer patients
    Wolf, Ido
    Ben-Baruch, Noa
    Shapira-Frommer, Ronnie
    Rizel, Shulamit
    Goldberg, Hadassa
    Yaal-Hahoshen, Neora
    Klein, Baruch
    Geffen, David B.
    Kaufman, Bella
    CANCER, 2008, 112 (04) : 731 - 736
  • [45] Prognostic impact of the 21-gene recurrence score in patients presenting with stage IV breast cancer.
    King, Tari A.
    Lyman, Jaclyn P.
    Gonen, Mithat
    Voci, Amy
    De Brot, Marina
    Boafa, Camilla
    Sing, Amy Pratt
    Hwang, Eun-Sil Shelley
    Alvarado, Michael
    Liu, Minetta C.
    Boughey, Judy Caroline
    McGuire, Kandace P.
    Van Poznak, Catherine H.
    Jacobs, Lisa K.
    Meszoely, Ingrid M.
    Krontiras, Helen
    Babiera, Gildy
    Norton, Larry
    Morrow, Monica
    Hudis, Clifford
    JOURNAL OF CLINICAL ONCOLOGY, 2013, 31 (15)
  • [46] The 21-Gene Recurrence Score Influences Treatment Recommendations for Patients With Node-Positive Breast Cancer
    Millien, Jeffanne
    Edwards, Claire
    Kaltman, Rebecca
    McSwain, Anita P.
    McGrail, Lisa
    Teal, Christine B.
    ANNALS OF SURGICAL ONCOLOGY, 2014, 21 : 82 - 83
  • [47] Prognostic impact of 21-gene recurrence score in patients with node negative breast cancer in China.
    Zeng, Yinduo
    Qin, Tao
    Li, Qian
    Chen, Kai
    Li, Shunrong
    Jin, Liang
    JOURNAL OF CLINICAL ONCOLOGY, 2018, 36 (15)
  • [48] COST-BENEFIT ANALYSIS OF A 21-GENE RECURRENCE SCORE FOR EARLY STAGE BREAST CANCER IN SINGAPORE
    de Lima, Lopes G.
    Chien, R.
    Hornberger, J.
    VALUE IN HEALTH, 2010, 13 (07) : A512 - A512
  • [49] 21-gene recurrence score® in patients with primary metastatic ER+HER2-breast cancer
    Barinoff, J.
    Anastasiadou, L.
    Brandi, C.
    Junker-Stein, A.
    Silbermann, J.
    Langenfeld, M.
    Fortmann, C.
    Thill, M.
    CANCER RESEARCH, 2017, 77
  • [50] The 21-Gene Recurrence Score in Special Histologic Subtypes of Breast Cancer A Population-Based Study
    Gulbahce, H. Evin
    Downs-Kelly, Erinn
    Herget, Kimberly A.
    Stoddard, Gregory J.
    ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE, 2022, 146 (04) : 478 - 484
12345