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- [37] Scar tissueCURRENT OPINION IN OTOLARYNGOLOGY & HEAD AND NECK SURGERY, 2010, 18 (04): : 261 - 265Jones, Nick
Scar tissue to lung cancer; pathways and treatment
被引：4
|作者：
Sapalidis, Konstantinos
[1
]
Sardeli, Chrysanthi
[2
]
Pavlidis, Efstathios
[1
]
Koimtzis, Georgios
[1
]
Koulouris, Charilaos
[1
]
Michalopoulos, Nikolaos
[1
]
Mantalovas, Stylianos
[1
]
Tsiouda, Theodora
[1
]
Passos, Ioannis
[1
]
Kosmidis, Christoforos
[1
]
Giannakidis, Dimitrios
[1
]
Surlin, Valeriu
[1
]
Katsaounis, Athanasios
[1
]
Alexandrou, Vyron
[1
]
Amaniti, Aikaterini
[3
]
Zarogoulidis, Paul
[1
,2
]
Huang, Haidong
[4
]
Li, Qiang
[4
]
Mogoanta, Stelian
[5
]
Kesisoglou, Isaac
[1
]
机构：
[1] Aristotle Univ Thessaloniki, AHEPA Univ Hosp, Med Sch, Dept Surg 3, Thessaloniki, Greece
[2] Aristotle Univ Thessaloniki, Fac Hlth Sci, Sch Med, Dept Pharmacol & Clin Pharmacol, Thessaloniki, Greece
[3] Aristotle Univ Thessaloniki, AHEPA Univ Hosp, Med Sch, Anaisthisiol Dept, Thessaloniki, Greece
[4] Tongji Univ, Shanghai East Hosp, Diagnost & Therapeut Ctr Resp Dis, Shanghai, Peoples R China
[5] Univ Med & Pharm Craiova, Fac Dent, Dept Surg, Craiova, Romania
来源：
关键词：
lung cancer;
scar tissue;
interstitial disease;
fibrosis;
pathways;
IDIOPATHIC PULMONARY-FIBROSIS;
EGFR MUTATION DETECTION;
LIQUID BIOPSY;
DISEASE;
PNEUMONITIS;
NSCLC;
OSIMERTINIB;
MECHANISMS;
CRIZOTINIB;
RESISTANCE;
D O I：
10.7150/jca.30300
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Lung cancer still remains diagnosed at a late stage although we have novel diagnostic techniques at our disposal. However; for metastatic disease we have novel therapies based on pharmacogenomics. Tumor heterogenity provides us different treatments. There are several reasons for carcinogenesis; fibrosis and scar tissue provides an environment that induces malignancy. In the current review we will try and elucidate the pathways involved from scar tissue to carcinogenesis.
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页码：810 / 818
页数：9
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