Effect of Surface Modification of Nano-Hydroxyapatite Particles on In Vitro Biocompatibility of Poly (ε-Caprolactone)-Matrix Composite Biomaterials

被引：13
|
作者：
Deng, C. [1 ,2 ]
Xiao, X.
Yao, N. [1 ]
Yang, X. B. [1 ]
Weng, J. [1 ]
机构：
[1] SW Jiaotong Univ, Sch Mat Sci & Engn, Key Lab Adv Technol Mat, Minist Educ, Chengdu 610031, Sichuan, Peoples R China
[2] Leshan Normal Univ, Leshan Inst Silicon Mat, Leshan, Peoples R China
来源：
INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS | 2011年 / 60卷 / 12期
关键词：
biocompatibility; nano-hydroxyapatite; silane coupling agents; surface modification; DISSOCIATIVE IONIZATION; SILANE; ADHESION;
D O I：
10.1080/00914037.2011.553847
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
Three silane coupling agents were employed to modify the surfaces of nano-hydroxyapatite particles. Alamar Blue activity and alkaline phosphatase assay on the surfaces of the modified n-HA/PCL composites were carefully examined. The results showed that the KH792 silane modification had positively impact in interaction between bone marrow cells, and it suggested this KH792 modified composite was basically biocompatible with bone cells of rats.
引用
收藏
页码：969 / 978
页数：10
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