Effect of Surface Modification of Nano-Hydroxyapatite Particles on In Vitro Biocompatibility of Poly (ε-Caprolactone)-Matrix Composite Biomaterials

被引：13
|
作者：
Deng, C. [1 ,2 ]
Xiao, X.
Yao, N. [1 ]
Yang, X. B. [1 ]
Weng, J. [1 ]
机构：
[1] SW Jiaotong Univ, Sch Mat Sci & Engn, Key Lab Adv Technol Mat, Minist Educ, Chengdu 610031, Sichuan, Peoples R China
[2] Leshan Normal Univ, Leshan Inst Silicon Mat, Leshan, Peoples R China
来源：
INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS | 2011年 / 60卷 / 12期
关键词：
biocompatibility; nano-hydroxyapatite; silane coupling agents; surface modification; DISSOCIATIVE IONIZATION; SILANE; ADHESION;
D O I：
10.1080/00914037.2011.553847
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
Three silane coupling agents were employed to modify the surfaces of nano-hydroxyapatite particles. Alamar Blue activity and alkaline phosphatase assay on the surfaces of the modified n-HA/PCL composites were carefully examined. The results showed that the KH792 silane modification had positively impact in interaction between bone marrow cells, and it suggested this KH792 modified composite was basically biocompatible with bone cells of rats.
引用
收藏
页码：969 / 978
页数：10
相关论文
共 50 条
  • [1] The effect of surface-modified nano-hydroxyapatite on biocompatibility of poly(ε-caprolactone)/hydroxyapatite nanocomposites
    Lee, Hong Jae
    Kim, Sung Eun
    Choi, Hyung Woo
    Kim, Chan Woo
    Kim, Kyung Ja
    Lee, Sang Cheon
    EUROPEAN POLYMER JOURNAL, 2007, 43 (05) : 1602 - 1608
  • [2] The effect of surface-modified nano-hydroxyapatite on biocompatibility of poly(Ε-caprolactone)/hydroxyapatite nanocomposites
    Lee, Hong Jae
    Kim, Sung Eun
    Choi, Hyung Woo
    Kim, Chan Woo
    Kim, Kyung Ja
    Lee, Sang Cheon
    European Polymer Journal, 2007, 43 (05): : 1602 - 1608
  • [3] In vivo biocompatibility and osteogenesis of electrospun poly(ε-caprolactone)-poly(ethylene glycol)-poly(ε-caprolactone)/nano-hydroxyapatite composite scaffold
    Fu, ShaoZhi
    Ni, PeiYan
    Wang, BeiYu
    Chu, BingYang
    Peng, JinRong
    Zheng, Lan
    Zhao, Xia
    Luo, Feng
    Wei, YuQuan
    Qian, ZhiYong
    BIOMATERIALS, 2012, 33 (33) : 8363 - 8371
  • [4] In Vitro Biocompatibility Assessment of Nano-Hydroxyapatite
    Kavasi, Rafaela-Maria
    Coelho, Catarina C.
    Platania, Varvara
    Quadros, Paulo A.
    Chatzinikolaidou, Maria
    NANOMATERIALS, 2021, 11 (05)
  • [5] Biocompatibility of Nano-hydroxyapatite/Polyetheretherketone Composite Materials with Osteoblasts Cultured in Vitro
    Wang, Lin
    Huang, Feijuan
    Wu, Zhengzhi
    Ma, Rui
    ADVANCES IN ENERGY SCIENCE AND ENVIRONMENT ENGINEERING, 2017, 1829
  • [6] Preparation and Characterization of Nano-Hydroxyapatite/Poly(ε-caprolactone)-Poly(ethylene glycol)-Poly(ε-caprolactone) Composite Fibers for Tissue Engineering
    Fu, ShaoZhi
    Wang, XiuHong
    Guo, Gang
    Shi, Shuai
    Liang, Hang
    Luo, Feng
    Wei, YuQuan
    Qian, ZhiYong
    JOURNAL OF PHYSICAL CHEMISTRY C, 2010, 114 (43): : 18372 - 18378
  • [7] Biocompatibility and physicochemical characteristics of poly(ε-caprolactone)/poly( lactide-co-glycolide)/nano-hydroxyapatite composite scaffolds for bone tissue engineering
    Li, Xin
    Zhang, Shujiang
    Zhang, Xiao
    Xie, Siyu
    Zhao, Guanghui
    Zhang, Lifen
    MATERIALS & DESIGN, 2017, 114 : 149 - 160
  • [8] In Vitro and Animal Study of Novel Nano-Hydroxyapatite/Poly(ε-Caprolactone) Composite Scaffolds Fabricated by Layer Manufacturing Process
    Heo, Su-Jin
    Kim, Seung-Eon
    Wei, Jie
    Kim, Dong Hwa
    Hyun, Young-Taek
    Yun, Hui-Suk
    Kim, Hyung Keun
    Yoon, Taek Rim
    Kim, Su-Hyang
    Park, Su-A
    Shin, Ji Won
    Shin, Jung-Woog
    TISSUE ENGINEERING PART A, 2009, 15 (05) : 977 - 989
  • [9] Preparation and Biocompatibility Study of Nano-Hydroxyapatite Composite Materials
    Wang, Lanlei
    Yang, Jiafeng
    Sun, Kangning
    Liu, Aihong
    Qiu, Liping
    Li, Aimin
    JOURNAL OF SCIENTIFIC CONFERENCE PROCEEDINGS, VOL 1, NOS. 2 AND 3, 2009, 1 (2-3): : 315 - +
  • [10] In vitro and in vivo biocompatibility of nano-hydroxyapatite/collagen composites
    Lin, XY
    Fan, HS
    Li, XD
    Tang, M
    Zhang, LL
    Tan, YF
    Xu, JR
    Zhang, XD
    ASBM6: ADVANCED BIOMATERIALS VI, 2005, 288-289 : 195 - 198
12345