OXIDATION OF FURSEMIDE BY PERMANGANATE IN AQUEOUS ALKALINE MEDIUM. A KINETIC STUDY

被引：0
|
作者：
Angadi, M. A. [1 ]
Tuwar, S. M. [1 ]
机构：
[1] Karnatak Sci Coll, Dept Chem, Dharwad 580001, Karnataka, India
来源：
OXIDATION COMMUNICATIONS | 2011年 / 34卷 / 03期
关键词：
kinetics; oxidation; fursemide; permanganate; ACID; MECHANISM; ARGININE;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Kinetics of oxidation of fursemide by alkaline permanganate was studied spectrophotometrically. Reaction was found to be first order in [permanganate] and fractional order in [fursemide]. The kinetics was independent on [OH(-)]. The added salt did not alter the rate of reaction. The oxidation products of fursemide were identified as furfuraldehyde and 4-chloro-2-amino-5-(amino-sulphonyl) benzoic acid. A suitable mechanism based on proton abstraction from the a-carbon atom of furfuryl moiety by permanganate was proposed as given below permanganate + fursemide (sic) complex complex (sic) free radical + manganate and other fast steps. Rate law was derived and verified. The equilibrium constant, K, and rate constant of the slow step, k, are evaluated and used to calculate the experimental rate constants.
引用
收藏
页码：555 / 565
页数：11
相关论文
共 50 条
  • [31] A kinetic study of the oxidation of formaldehyde by the octacyanomolybdate(V) ion in aqueous alkaline medium
    C. Robert Dennis
    I. M. Potgieter
    S. S. Basson
    Reaction Kinetics, Mechanisms and Catalysis, 2011, 104 : 1 - 7
  • [32] MECHANISM OF THE OSMIUM(VIII)-CATALYSED OXIDATION OF FURSEMIDE BY ALKALINE HEXACYANOFERRATE(III) AND ANALYSIS OF FURSEMIDE BY A KINETIC AND CATALYTIC METHOD
    Billalli, H. B.
    Sharanabasamma, K.
    Tuwar, S. M.
    PROGRESS IN REACTION KINETICS AND MECHANISM, 2010, 35 (04) : 347 - 367
  • [33] Oxidation of ninhydrin by sodium N-bromo-p-toluenesulphonamide in alkaline medium.: A kinetic and mechanistic study
    Puttaswamy
    Ramachandrappa, R
    OXIDATION COMMUNICATIONS, 2000, 23 (04): : 599 - 608
  • [34] Kinetic Study of the Oxidation of Glycine by Permanganate Ions in Acid Medium
    Insausti, M. J.
    Mata-Perez, F.
    Alvarez-Macho, M. P.
    Collection of Czechoslovak Chemical Communications, 61 (02):
  • [35] OXIDATION OF VALINE AND 2-AMINOISOBUTYRIC ACID BY DITELLURATOCUPRATE(III) IN ALKALINE MEDIUM. A KINETIC AND MECHANISTIC STUDY
    Shan, Jinhuan
    Li, Yi
    Han, Jin
    Zhang, Ziwei
    OXIDATION COMMUNICATIONS, 2013, 36 (03): : 720 - 729
  • [36] OXIDATION OF THIOPHENOL BY HEXACYANOFERRATE(III) IN ACID MEDIUM. A KINETIC STUDY
    Dasgupta, G.
    Mahanti, M. K.
    OXIDATION COMMUNICATIONS, 2013, 36 (02): : 302 - 306
  • [37] Oxidative degradation of choline chloride by diperiodatonickelate(IV) in aqueous alkaline medium. A kinetic approach
    Kulkarni, RM
    Bilehal, DC
    Nandibewoor, ST
    OXIDATION COMMUNICATIONS, 2005, 28 (01): : 115 - 125
  • [38] Oxidation of mandelic acid by alkaline potassium permanganate. A kinetic study
    Panari, RG
    Chougale, RB
    Nandibewoor, ST
    JOURNAL OF PHYSICAL ORGANIC CHEMISTRY, 1998, 11 (07) : 448 - 454
  • [39] Free radical intervention in the oxidation of nicotinamide by alkaline permanganate - A kinetic study
    Pol, PD
    Mahesh, RT
    Nandibewoor, ST
    JOURNAL OF CHEMICAL RESEARCH-S, 2002, (11): : 533 - 534
  • [40] Oxidation of (+)-(R)-pantothenic acid by aqueous alkaline potassium permanganate: A kinetic and mechanistic approach
    Desai, S.M.
    Halligudi, N.N.
    Mavalangi, S.K.
    Nandibewoor, S.T.
    Zeitschrift fur Physikalische Chemie, 2002, 216 (06): : 803 - 814
12345