Mixed States in Early-Onset Bipolar Disorder

被引：15
|
作者：
Saxena, Kirti [1 ,2 ]
Kurian, Sherin [1 ,2 ]
Saxena, Johanna [1 ,2 ]
Goldberg, Adam [3 ]
Chen, Eugenia [1 ]
Simonetti, Alessio [1 ,4 ,5 ,6 ]
机构：
[1] Baylor Coll Med, Menninger Dept Psychiat & Behav Sci, 1 Baylor Plaza, Houston, TX 77030 USA
[2] Texas Childrens Hosp, Dept Psychiat, Houston, TX 77030 USA
[3] Univ Texas Hlth Sci Ctr Houston, McGovern Med Sch, Dept Psychiat & Behav Sci, 1941 East Rd, Houston, TX 77054 USA
[4] Sapienza Univ Rome, Dept Neurol & Psychiat, Rome, Italy
[5] Ctr Lucio Bini, Rome, Italy
[6] Baylor Coll Med, Dept Psychiat, 1977 Butler Blvd,Suite E4-400, Houston, TX 77030 USA
来源：
PSYCHIATRIC CLINICS OF NORTH AMERICA | 2020年 / 43卷 / 01期
关键词：
Mixed states; Bipolar disorder; Children; Adolescents; Diagnosis; Comorbidity; Treatment; OPEN-LABEL TRIAL; I DISORDER; DOUBLE-BLIND; DIVALPROEX SODIUM; CHILDREN; ADOLESCENTS; PLACEBO; LITHIUM; DEPRESSION; ARIPIPRAZOLE;
D O I：
10.1016/j.psc.2019.10.009
中图分类号：
R749 [精神病学];
学科分类号：
100205 ;
摘要：
Pediatric bipolar disorder (PBD) is a severe and chronic illness. The occurrence of mixed symptoms might add further risk of recurrence of treatment resistance and suicidality. Early recognition and treatment of mixed symptoms might prevent illness progression and development of suicide attempts. This article provides an update on the epidemiology, clinical profile, and treatment of youth with PBD with mixed states. Mixed states in PBD are characterized by higher rates of suicide and more chronic symptoms, and are associated with younger age of onset and greater comorbidity. A careful assessment for mixed states using standardized criteria is essential.
引用
收藏
页码：95 / +
页数：18
相关论文
共 50 条
  • [21] Lithium prophylaxis in early-onset Bipolar disorder: a descriptive study
    Selvarajan, Sandhiya
    Manohar, Harshini
    Das, Saibal
    Sakkarabani, Priyanka
    Kandasamy, Preeti
    ASIAN JOURNAL OF PSYCHIATRY, 2019, 44 : 172 - 174
  • [22] Onset pattern and time course of prodromal symptoms in early-onset bipolar disorder
    Correll, CU
    Penzner, J
    Kafantaris, V
    Nakayama, E
    Auther, A
    Lencz, T
    Malhotra, AK
    Kane, JM
    Cornblatt, BA
    BIPOLAR DISORDERS, 2005, 7 : 44 - 44
  • [23] Early-onset and very-early-onset bipolar disorder: distinct or similar clinical conditions?
    Propper, Lukas
    Ortiz, Abigail
    Slaney, Claire
    Garnham, Julie
    Ruzickova, Martina
    Calkin, Cynthia V.
    O'Donovan, Claire
    Hajek, Tomas
    Alda, Martin
    BIPOLAR DISORDERS, 2015, 17 (08) : 814 - 820
  • [24] Early-onset and Very-early-onset Bipolar Disorder: Distinct or Similar Clinical Conditions?
    Propper, Lukas
    O'Donovan, Claire
    Ruzickova, Martina
    Calkin, Cynthia
    Hajek, Tomas
    Ortiz, Abigail
    Slaney, Claire
    Garnham, Julie
    Alda, Martin
    NEUROPSYCHOPHARMACOLOGY, 2013, 38 : S398 - S399
  • [25] Prognosis of Early-onset Bipolar Disorder Compared to Early-onset Schizophrenia and Healthy Controls in a Nationwide Register Based Study
    Laursen, Mathilde Frahm
    Licht, Rasmus
    Valentin, Jan Brink
    Correll, Christoph
    Nielsen, Rene Ersnt
    EARLY INTERVENTION IN PSYCHIATRY, 2018, 12 : 152 - 152
  • [26] Behavioral activation, inhibition and mood symptoms in early-onset bipolar disorder
    Biuckians, Adrine
    Miklowitz, David J.
    Kim, Eunice Y.
    JOURNAL OF AFFECTIVE DISORDERS, 2007, 97 (1-3) : 71 - 76
  • [27] Use of Suvorexant for Sleep Regulation in an Adolescent with Early-Onset Bipolar Disorder
    Prieto, Diana I.
    Zehgeer, Asima A.
    Connor, Daniel F.
    JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY, 2019, 29 (05) : 395 - 395
  • [28] Genome-Wide Association Study on Early-Onset Bipolar Disorder
    Jamain, Stephane
    Cichon, Sven
    Etain, Bruno
    Muehleisen, Thomas W.
    Georgi, Alexander
    Zidane, Nora
    Herms, Stefan
    Mattheisen, Manuel
    Priebe, Lutz
    Mathieu, Flavie
    Henry, Chantal
    Boland, Anne
    Zelenika, Diana
    Gut, Ivo
    Bellivier, Frank
    Rietschel, Marcella
    Noethen, Markus M.
    Leboyer, Marion
    BIOLOGICAL PSYCHIATRY, 2009, 65 (08) : 6S - 6S
  • [29] Childhood ADHD and Early-Onset Bipolar Disorder Comorbidity: A Case Report
    Tatsiopoulou, Paraskevi
    Porfyri, Georgia-Nektaria
    Bonti, Eleni
    Diakogiannis, Ioannis
    BRAIN SCIENCES, 2020, 10 (11) : 1 - 13
  • [30] EARLY-ONSET AND LATE-ONSET BIPOLAR AFFECTIVE-DISORDER - A STUDY OF HETEROGENEITY
    YAN, SM
    LUXI, X
    IRCS MEDICAL SCIENCE-BIOCHEMISTRY, 1985, 13 (04): : 328 - 329
12345