2D materials for bone therapy

被引：37

作者：

Wang, Xiangjiang ^{[1
]}

Han, Xianjing ^{[1
]}

Li, Chaozhou ^{[2
]}

Chen, Zhi ^{[2
]}

Huang, Hao ^{[2
]}

Chen, Jindong ^{[1
]}

Wu, Chenshuo ^{[2
]}

Fan, Taojian ^{[3
]}

Li, Tianzhong ^{[6
]}

Huang, Weichun ^{[4
]}

Al-Hartomy, Omar A. ^{[7
]}

Al-Ghamdi, Ahmed ^{[7
]}

Wageh, Abdullah Swelm. ^{[7
]}

Zheng, Fei ^{[2
]}

Al-Sehemi, G. ^{[8
]}

Wang, Guiqing ^{[1
]}

Xie, Zhongjian ^{[5
,6
]}

Zhang, Han ^{[2
]}

机构：

[1] Guangzhou Med Univ, Qingyuan Peoples Hosp, Affiliated Hosp 6, Qingyuan 511518, Guangdong, Peoples R China

[2] Shenzhen Univ, Int Collaborat Lab Mat Optoelect Sci & Technol 2D, Shenzhen Engn Lab Phosphorene & Optoelect, Minist Educ,Coll Optoelect Engn, Shenzhen 518060, Peoples R China

[3] Shenzhen Technol Univ, Coll Hlth Sci & Environm Engn, Shenzhen 518118, Peoples R China

[4] Nantong Univ, Sch Chem & Chem Engn, Nantong Key Lab Intelligent & New Energy Mat, Nantong 226019, Jiangsu, Peoples R China

[5] Shenzhen Childrens Hosp, Inst Pediat, Shenzhen 518038, Guangdong, Peoples R China

[6] Shenzhen Int Inst Biomed Res, Shenzhen 518116, Guangdong, Peoples R China

[7] King Abdulaziz Univ, Fac Sci, Dept Phys, Jeddah 21589, Saudi Arabia

[8] King Khalid Univ, Res Ctr Adv Mat Sci RCAMS, Fac Sci, Dept Chem, POB 9004, Abha 61413, Saudi Arabia

来源：

ADVANCED DRUG DELIVERY REVIEWS | 2021年 / 178卷 / 178期

关键词：

2D materials; Bone tissue engineering; Joint lubrication; Antibacterial; Bone tumors; Osteoarthritis; BLACK PHOSPHORUS NANOPARTICLES; MESENCHYMAL STEM-CELLS; OF-THE-ART; GRAPHENE-OXIDE; PHOTOTHERMAL THERAPY; IN-VIVO; ANTIBACTERIAL ACTIVITY; MOLYBDENUM-DISULFIDE; DRUG-DELIVERY; CARTILAGE DEGENERATION;

D O I：

10.1016/j.addr.2021.113970

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Due to their prominent physicochemical properties, 2D materials are broadly applied in biomedicine. Currently, 2D materials have achieved great success in treating many diseases such as cancer and tissue engineering as well as bone therapy. Based on their different characteristics, 2D materials could function in various ways in different bone diseases. Herein, the application of 2D materials in bone tissue engineering, joint lubrication, infection of orthopedic implants, bone tumors, and osteoarthritis are firstly reviewed comprehensively together. Meanwhile, different mechanisms by which 2D materials function in each disease reviewed below are also reviewed in detail, which in turn reveals the versatile functions and application of 2D materials. At last, the outlook on how to further broaden applications of 2D materials in bone therapies based on their excellent properties is also discussed. (c) 2021 Elsevier B.V. All rights reserved.

引用

页数：24

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