Wound dressing from polyvinyl alcohol/chitosan electrospun fiber membrane loaded with OH-CATH30 nanoparticles

被引：125
|
作者：
Zou, Pengfei [1 ]
Lee, Wen-Hui [2 ,3 ]
Gao, Zhiqin [3 ]
Qin, Di [3 ]
Wang, Yuxia [1 ]
Liu, Jiao [1 ]
Sun, Tongyi [3 ]
Gao, Yuanyuan [1 ]
机构：
[1] Weifang Med Univ, Sch Pharm, Baotong Rd, Weifang 261053, Shandong, Peoples R China
[2] Chinese Acad Sci, Kunming Inst Zool, Key Lab Anim Models & Human Dis Mech, Key Lab Bioact Peptide Yunnan Prov, Kunming 650223, Yunnan, Peoples R China
[3] Weifang Med Univ, Sch Biosci & Technol, Key Lab Biol Med Univ Shandong Prov, Baotong Rd, Weifang 261053, Shandong, Peoples R China
来源：
CARBOHYDRATE POLYMERS | 2020年 / 232卷 / 232期
基金：
中国国家自然科学基金;
关键词：
OH-CATH30; PVA; Wound healing; Nanofibers; Nanoparticles; ANTIMICROBIAL PEPTIDE OH-CATH30; IN-VITRO; NANOFIBROUS MEMBRANE; SILVER NANOPARTICLES; EFFICIENT STRATEGY; ANTIBACTERIAL; DRUG; ALGINATE; MATS; FABRICATION;
D O I：
10.1016/j.carbpol.2019.115786
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Novel nanomaterials have been developed for antimicrobial and wound healing applications. Here, we report the preparation of a polyvinyl alcohol/chitosan (PVA/CS) nanofiber with carboxymethyl chitosan nanoparticles (CMCS-OH30 NPs) encapsulating the antibacterial peptide OH-CATH30 (OH-30). The PVA/CS nanofibers containing OH-30 NPs (NP-30-NFs) obtained via electrospinning could achieve a secondary embedded OH-30. The effect of NP-30-NFs on the release of OH-30 was investigated through high-performance liquid chromatography. The antibacterial activities of NP-30-NFs against Escherichia coli and Staphylococcus aureus were studied by bacterial plate counting. NP-30-NFs containing different concentrations of NPs were applied to mouse skin wounds to determine their effectiveness in promoting wound healing. Results showed that NP-30-NFs exhibited antibacterial properties and promoted skin wound healing.
引用
收藏
页数：10
相关论文
共 50 条
  • [21] Sulfanilamide and silver nanoparticles-loaded polyvinyl alcohol-chitosan composite electrospun nanofibers: Synthesis and evaluation on synergism in wound healing
    Ganesh, Mani
    Aziz, Abidov Sch
    Ubaidulla, Udumansha
    Hemalatha, Pushparaj
    Saravanakumar, Arthanari
    Ravikumar, Rramaswamy
    Peng, Mei Mei
    Choi, Eun Young
    Jang, Hyun Tae
    JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY, 2016, 39 : 127 - 135
  • [22] Ag@MOF-loaded chitosan nanoparticle and polyvinyl alcohol/sodium alginate/chitosan bilayer dressing for wound healing applications
    Zhang, Meng
    Wang, Guohui
    Wang, Dong
    Zheng, Yuqi
    Li, Yanxin
    Meng, Wenqiao
    Zhang, Xin
    Du, Feifan
    Lee, Shaoxiang
    INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2021, 175 : 481 - 494
  • [23] Gel characterisation and in vivo evaluation of minocycline-loaded wound dressing with enhanced wound healing using polyvinyl alcohol and chitosan
    Sung, Jung Hoon
    Hwang, Ma-Ro
    Kim, Jong Oh
    Lee, Jeong Hoon
    Kim, Yong Il
    Kim, Jeong Hoon
    Chang, Sun Woo
    Jin, Sung Giu
    Kim, Jung Ae
    Lyoo, Won Seok
    Han, Sung Soo
    Ku, Sae Kwang
    Yong, Chul Soon
    Choi, Han-Gon
    INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2010, 392 (1-2) : 232 - 240
  • [24] Microwave-Assisted Synthesis of Chitosan/Polyvinyl Alcohol Silver Nanoparticles Gel for Wound Dressing Applications
    Nguyen Thi Hiep
    Huynh Chan Khon
    Vo Van Thanh Niem
    Vo Van Toi
    Tran Ngoc Quyen
    Nguyen Dai Hai
    Mai Ngoc Tuan Anh
    INTERNATIONAL JOURNAL OF POLYMER SCIENCE, 2016, 2016
  • [25] Synthesis and Characterization of Carboxymethyl Chitosan/Polyvinyl Alcohol Containing Zinc Oxide Nanoparticles as Hydrogel Wound Dressing
    Bakhtiari, Kimia
    Kashanian, Soheila
    Mohamadinooripoor, Rezvan
    Rashidi, Khodabakhsh
    Sajadimajd, Soraya
    Omidfar, Kobra
    FIBERS AND POLYMERS, 2024, 25 (11) : 4199 - 4213
  • [26] Fabrication and characterization of glycerol/chitosan/polyvinyl alcohol-based transparent hydrogel films loaded with silver nanoparticles for antibacterial wound dressing applications
    Samadi, Ali
    Azandeh, Saeed
    Orazizadeh, Mahmoud
    Bayati, Vahid
    Rafienia, Mohammad
    Karami, Masoud Ali
    ADVANCED BIOMEDICAL RESEARCH, 2021, 10 (01): : 4
  • [27] Fabrication and characterisation of chitosan/polyvinyl alcohol-based transparent hydrogel films loaded with silver nanoparticles and sildenafil citrate for wound dressing applications
    Samadi, Ali
    Azandeh, Saeed
    Orazizadeh, Mahmoud
    Bayati, Vahid
    Rafienia, Mohammad
    Karami, Masoud Ali
    MATERIALS TECHNOLOGY, 2022, 37 (05) : 355 - 365
  • [28] Fabrication of electrospun polycaprolactone based membrane coated with curcumin chitosan nanoparticles and gelatin for wound dressing application
    Nguyen, Thao-Trang
    Vong, Long Binh
    Ha, Nhi Nguyen-yen
    Nguyen-Ngoc, Bao-Han
    Nguyen, Van Khiem
    Doan, Hoan Ngoc
    Dang, Nhi Ngoc-Thao
    Phan, Ke-Son
    To, Xunag Thang
    Mai-Thi, Thu-Trang
    Ta, Hanh Thi-Kieu
    Ha, Phuong-Thu
    Trinh, Nhu- Thuy
    Nguyen, Thi-Hiep
    MATERIALS TODAY COMMUNICATIONS, 2024, 40
  • [29] Antibacterial wound dressing electrospun nanofibrous material from polyvinyl alcohol, honey and Curcumin longa extract
    Shahid, Md. Abdus
    Ali, Ayub
    Uddin, Md. Nur
    Miah, Sumon
    Islam, Syed Maminul
    Mohebbullah, Md.
    Jamal, Mohammad Salman Ibna
    JOURNAL OF INDUSTRIAL TEXTILES, 2021, 51 (03) : 455 - 469
  • [30] Preparation of Polyvinyl Alcohol/Asiaticoside/Chitosan Membrane Nano-composite Using Electrospinning Technique for Wound Dressing
    Raharjo, Arifin Budi
    Putra, Richo Dwi Andika
    Indayaningsih, Nanik
    Srifiana, Yudi
    Hardiansyah, Andri
    Irmawati, Yuyun
    Widodo, Henry
    Destyorini, Fredina
    PROCEEDINGS OF THE 5TH INTERNATIONAL SYMPOSIUM ON FRONTIER OF APPLIED PHYSICS (ISFAP 2019), 2020, 2256
12345