Liebeskind-Srogl cross coupling mediated synthesis of verbenachalcone

被引:9
|
作者
Dandepally, Srinivasa Reddy [1 ]
Williams, Alfred L. [1 ,2 ]
机构
[1] N Carolina Cent Univ, Biomfg Res Inst & Technol Enterprise, Durham, NC 27707 USA
[2] N Carolina Cent Univ, Dept Pharmaceut Sci, Coll Sci Technol, Durham, NC 27707 USA
关键词
Natural product synthesis; Verbenachalcone; Liebeskind-Srogl cross coupling; Ullmann ether synthesis; NEURITE OUTGROWTH; DIARYL ETHER; LITTORACHALCONE;
D O I
10.1016/j.tetlet.2010.08.073
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A flexible and scalable total synthesis of verbenachalcone is achieved in eight linear steps from cheap commercially available starting material, 3-(4-hydroxyphenyl)propanoic acid. (C) 2010 Elsevier Ltd. All rights reserved.
引用
收藏
页码:5753 / 5756
页数:4
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