Human progeroid syndromes (PSs) include a group of genetic "premature aging" diseases that affect a variety of organ systems. Bone diseases are common sequelae of patients diagnosed with PSs. Teriparatide therapy is recommended for elderly men with low bone mineral density (BMD; T-score < -2.5) and at least 1 fragility fracture who are unable to tolerate bisphosphonates. We describe a 20-yr-old patient affected by PS and severe osteoporosis complicated with femoral fracture. The patient experienced a significant improvement in lumbar spine BMD after treatment with teriparatide.
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Innsbruck Med Univ, Clin Dept Internal Med, Clin Div Gen Internal Med, Innsbruck, AustriaInnsbruck Med Univ, Clin Dept Internal Med, Clin Div Gen Internal Med, Innsbruck, Austria
Finkenstedt, G.
Finkenstedt, A.
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Innsbruck Med Univ, Clin Dept Internal Med, Clin Div Gen Internal Med, Innsbruck, AustriaInnsbruck Med Univ, Clin Dept Internal Med, Clin Div Gen Internal Med, Innsbruck, Austria
Finkenstedt, A.
Gasser, R. W.
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Innsbruck Med Univ, Clin Dept Internal Med, Clin Div Gen Internal Med, Innsbruck, AustriaInnsbruck Med Univ, Clin Dept Internal Med, Clin Div Gen Internal Med, Innsbruck, Austria
Gasser, R. W.
Götsch, C.
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Innsbruck Med Univ, Clin Dept Internal Med, Clin Div Gen Internal Med, Innsbruck, AustriaInnsbruck Med Univ, Clin Dept Internal Med, Clin Div Gen Internal Med, Innsbruck, Austria
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Univ Texas, Hlth Sci Ctr, Dept Family & Community Med, San Antonio, TX 78285 USAUniv Texas, Hlth Sci Ctr, Dept Family & Community Med, San Antonio, TX 78285 USA
Bazaldua, OV
Bruder, J
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机构:Univ Texas, Hlth Sci Ctr, Dept Family & Community Med, San Antonio, TX 78285 USA