Complicated Osteoporosis in Progeroid Syndrome: Treatment With Teriparatide

被引：0
|
作者：
Iglesias Bolanos, Paloma [1 ]
Guijarro de Armas, Guadalupe [1 ]
Civantos Modino, Soraya [1 ]
Vega Pinero, Belen [1 ]
Pavon de Paz, Isabel [1 ]
Monereo Megias, Susana [1 ]
机构：
[1] Getafe Univ Hosp, Dept Endocrinol, Madrid 28007, Spain
来源：
JOURNAL OF CLINICAL DENSITOMETRY | 2012年 / 15卷 / 01期
关键词：
Fracture; osteoporosis; progeroid syndrome; teriparatide; MODEL;
D O I：
10.1016/j.jocd.2011.10.001
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Human progeroid syndromes (PSs) include a group of genetic "premature aging" diseases that affect a variety of organ systems. Bone diseases are common sequelae of patients diagnosed with PSs. Teriparatide therapy is recommended for elderly men with low bone mineral density (BMD; T-score < -2.5) and at least 1 fragility fracture who are unable to tolerate bisphosphonates. We describe a 20-yr-old patient affected by PS and severe osteoporosis complicated with femoral fracture. The patient experienced a significant improvement in lumbar spine BMD after treatment with teriparatide.
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页码：116 / 119
页数：4
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