Accumulation of amino-terminally truncated and modified amyloid-β peptide in the brain and its impact on amyloid pathology of Alzheimer's disease

被引:0
|
作者
Iwata, Nobuhisa [1 ]
Tsubuki, Satoshi [1 ]
Higuchi, Makoto [1 ,2 ]
Staufenbiel, Matthias [3 ]
Saido, Takaomi C. [1 ]
机构
[1] RIKEN BSI, Lab Proteolyt Neurosci, Wako, Saitama 3510198, Japan
[2] Natl Inst Radiol Sci, Mol Imaging Ctr, Chiba 2638555, Japan
[3] Novartis Inst Biomed Res Basel, CH-4002 Basel, Switzerland
关键词
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
引用
收藏
页码:114P / 114P
页数:1
相关论文
共 50 条
  • [31] Modelling Copper Binding to the Amyloid-β Peptide in Alzheimer's Disease
    Epa, V. Chandana
    Streltsov, Victor A.
    Varghese, Joseph N.
    AUSTRALIAN JOURNAL OF CHEMISTRY, 2010, 63 (03) : 345 - 349
  • [32] Intraneuronal β-amyloid accumulation and synapse pathology in Alzheimer's disease
    Gouras, Gunnar K.
    Tampellini, Davide
    Takahashi, Reisuke H.
    Capetillo-Zarate, Estibaliz
    ACTA NEUROPATHOLOGICA, 2010, 119 (05) : 523 - 541
  • [33] Intraneuronal β-amyloid accumulation and synapse pathology in Alzheimer’s disease
    Gunnar K. Gouras
    Davide Tampellini
    Reisuke H. Takahashi
    Estibaliz Capetillo-Zarate
    Acta Neuropathologica, 2010, 119 : 523 - 541
  • [34] Biochemical stages of amyloid-β peptide aggregation and accumulation in the human brain and their association with symptomatic and pathologically preclinical Alzheimer's disease
    Upadhaya, Ajeet Rijal
    Kosterin, Irina
    Kumar, Sathish
    von Arnim, Christine A. F.
    Yamaguchi, Haruyasu
    Faendrich, Marcus
    Walter, Jochen
    Thal, Dietmar Rudolf
    BRAIN, 2014, 137 : 887 - 903
  • [35] Impact of nanoplastics on Alzheimer 's disease: Enhanced amyloid-β peptide aggregation and augmented neurotoxicity
    Gou, Xiaoli
    Fu, Yongchun
    Li, Juan
    Xiang, Juan
    Yang, Minghui
    Zhang, Yi
    JOURNAL OF HAZARDOUS MATERIALS, 2024, 465
  • [36] Restored degradation of the Alzheimer's amyloid-β peptide by targeting amyloid formation
    Crouch, Peter J.
    Tew, Deborah J.
    Du, Tai
    Nguyen, Diem Ngoc
    Caragounis, Aphrodite
    Filiz, Gulay
    Blake, Rachel E.
    Trounce, Ian A.
    Soon, Cynthia P. W.
    Laughton, Katrina
    Perez, Keyla A.
    Li, Qiao-Xin
    Cherny, Robert A.
    Masters, Colin L.
    Barnham, Kevin J.
    White, Anthony R.
    JOURNAL OF NEUROCHEMISTRY, 2009, 108 (05) : 1198 - 1207
  • [37] Perivascular drainage of amyloid-β peptides from the brain and its failure in cerebral amyloid angiopathy and Alzheimer's disease
    Weller, Roy O.
    Subash, Malavika
    Preston, Stephen D.
    Mazanti, Ingrid
    Carare, Roxana O.
    BRAIN PATHOLOGY, 2008, 18 (02) : 253 - 266
  • [38] Amyloid-β Immunotherapy for Alzheimer's Disease
    Fu, H. J.
    Liu, B.
    Frost, J. L.
    Lemere, C. A.
    CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS, 2010, 9 (02) : 197 - 206
  • [39] Role of amyloid-β in Alzheimer's disease
    Smith, MA
    Perry, G
    INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, 2005, 86 (03) : 131 - 131
  • [40] Intracellular amyloid-β in Alzheimer's disease
    LaFerla, Frank M.
    Green, Kim N.
    Oddo, Salvatore
    NATURE REVIEWS NEUROSCIENCE, 2007, 8 (07) : 499 - 509