Preparation and characterization of magnetic chitosan particles for hyperthermia application

被引:72
|
作者
Park, JH
Im, KH
Lee, SH
Kim, DH
Lee, DY
Lee, YK
Kim, KM
Kim, KN
机构
[1] Yonsei Univ, Coll Dent, Res Inst Dent Biomat & Bioengn, Seoul 120752, South Korea
[2] Yonsei Univ, Coll Dent, Dept Dent Biomat & Bioengn, Seoul 120752, South Korea
[3] Yonsei Univ, Coll Dent, Brain Korea Project Med Sci 21, Seoul 120752, South Korea
关键词
barium ferrite; coercivity; heating rate; hyperthermia; chitosan; saturation magnetization; toxicity;
D O I
10.1016/j.jmmm.2005.02.027
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
The size and shape of magnetic chitosan particles were found to be dependent on both the barium ferrite/chitosan (BF/C) ratio and viscosity of a chitosan solution. The saturation magnetization of magnetic chitosan particles varied directly with the BF/C ratio, while coercivity remained almost constant. Notably, incorporated chitosan was shown to exert substantial activity with regard to low cytotoxicity and high heating rate. (c) 2005 Published by Elsevier B.V.
引用
收藏
页码:328 / 333
页数:6
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