Complete remission of advanced hepatocellular carcinoma by radiofrequency ablation after sorafenib therapy

被引：8
|
作者：
Park, Jung Gil [1 ]
Park, Soo Young [2 ]
Lee, Hye Won [3 ]
机构：
[1] CHA Univ, Gumi CHA Med Ctr, Dept Internal Med, Div Gastroenterol & Hepatol, Gumi 730728, South Korea
[2] Kyungpook Natl Univ, Sch Med, Dept Internal Med, Div Gastroenterol & Hepatol, Daegu 700721, South Korea
[3] Kyungpook Natl Univ, Sch Med, Dept Pathol, Daegu 700721, South Korea
来源：
WORLD JOURNAL OF GASTROENTEROLOGY | 2015年 / 21卷 / 08期
关键词：
Hepatocellular carcinoma; Radiofrequency ablation; Sorafenib; Down-staging; Complete remission; PHASE-II; COMBINATION; TRIAL;
D O I：
10.3748/wjg.v21.i8.2568
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Sorafenib, a potent multikinase inhibitor, lead to a significant improvement in progression free survival and overall survival in patients with advanced hepatocellular carcinoma (HCC). Though sorafenib has proven its efficacy in advanced stage HCC, there are limited reports on the role of sorafenib allowing for curative treatment by down-staging. We herein report a case of advanced HCC with vascular invasion, which showed treatment response by sorafenib therapy as to allow for radiofrequency ablation as curative treatment. The patient was followed-up for 6 mo without recurrence with continued sorafenib therapy.
引用
收藏
页码：2568 / 2572
页数：5
相关论文
共 50 条
  • [21] Sustained Remission Over 36 Months of Advanced Hepatocellular Carcinoma After Short-Term Sorafenib Therapy
    Ahn, Sun Young
    Lee, Hyun Seok
    Kweon, Young Oh
    Tak, Won Young
    Park, Soo Young
    DIGESTIVE DISEASES AND SCIENCES, 2013, 58 (05) : 1428 - 1432
  • [22] Sustained Remission Over 36 Months of Advanced Hepatocellular Carcinoma After Short-Term Sorafenib Therapy
    Sun Young Ahn
    Hyun Seok Lee
    Young Oh Kweon
    Won Young Tak
    Soo Young Park
    Digestive Diseases and Sciences, 2013, 58 : 1428 - 1432
  • [23] Liver resection for recurrent hepatocellular carcinoma after radiofrequency ablation therapy
    Yamagishi, Shunsuke
    Midorikawa, Yutaka
    Nakayama, Hisashi
    Higaki, Tokio
    Moriguchi, Masamichi
    Aramaki, Osamu
    Yamazaki, Shintaro
    Tsuji, Shingo
    Takayama, Tadatoshi
    HEPATOLOGY RESEARCH, 2019, 49 (04) : 432 - 440
  • [24] Hepatocutaneous fistula: a complication after radiofrequency ablation therapy for hepatocellular carcinoma
    Huang, Hsu-Kai
    Lin, Chien-Hua
    Hsu, Chia-Chun
    Yu, Jyh-Cherng
    Liu, Yao-Chi
    Chen, Teng-Wei
    Hsieh, Chung-Bao
    NEW ZEALAND MEDICAL JOURNAL, 2007, 120 (1255) : 45 - 50
  • [25] Local recurrence of hepatocellular carcinoma after radiofrequency ablation associates with the safety margin of the complete ablation
    Nakazawa, T
    HEPATOLOGY, 2005, 42 (04) : 383A - 384A
  • [26] Impact of surgical treatment after sorafenib therapy for advanced hepatocellular carcinoma
    Takeyama, Hideaki
    Beppu, Toru
    Higashi, Takaaki
    Kaida, Takayoshi
    Arima, Kota
    Taki, Katsunobu
    Imai, Katsunori
    Nitta, Hidetoshi
    Hayashi, Hiromitsu
    Nakagawa, Shigeki
    Okabe, Hirohisa
    Hashimoto, Daisuke
    Chikamoto, Akira
    Ishiko, Takatoshi
    Tanaka, Motohiko
    Sasaki, Yutaka
    Baba, Hideo
    SURGERY TODAY, 2018, 48 (04) : 431 - 438
  • [27] Impact of surgical treatment after sorafenib therapy for advanced hepatocellular carcinoma
    Hideaki Takeyama
    Toru Beppu
    Takaaki Higashi
    Takayoshi Kaida
    Kota Arima
    Katsunobu Taki
    Katsunori Imai
    Hidetoshi Nitta
    Hiromitsu Hayashi
    Shigeki Nakagawa
    Hirohisa Okabe
    Daisuke Hashimoto
    Akira Chikamoto
    Takatoshi Ishiko
    Motohiko Tanaka
    Yutaka Sasaki
    Hideo Baba
    Surgery Today, 2018, 48 : 431 - 438
  • [28] Long-term follow-up of complete remission of advanced hepatocellular carcinoma following sorafenib therapy: A case report
    Park, Jung Gil
    Tak, Won Young
    Park, Soo Young
    Kweon, Young Oh
    Jang, Se Young
    Lee, Soo Hyun
    Lee, Yu Rim
    Jang, Sun Kyung
    Hur, Keun
    Lee, Heon Ju
    ONCOLOGY LETTERS, 2017, 14 (04) : 4853 - 4856
  • [29] Recurrence after radiofrequency ablation for hepatocellular carcinoma
    Shiina, S
    Teratani, T
    Sato, S
    Tateishi, R
    Kinbara, T
    Kanda, M
    Ishikawa, T
    Fujishima, T
    Akamatsu, M
    Obi, S
    Yoshida, H
    Koike, Y
    Imamura, M
    Hamarama, K
    Yoshida, H
    Kawabe, T
    Omata, M
    GASTROENTEROLOGY, 2003, 124 (04) : A774 - A774
  • [30] Hemobilia after radiofrequency ablation of hepatocellular carcinoma
    Rhim, Hyunchul
    Lim, Hyo K.
    Kim, Young-Sun
    Choi, Dongil
    Lee, Kyu Taek
    ABDOMINAL IMAGING, 2007, 32 (06): : 719 - 724
12345