Complete remission of advanced hepatocellular carcinoma by radiofrequency ablation after sorafenib therapy

被引:8
|
作者
Park, Jung Gil [1 ]
Park, Soo Young [2 ]
Lee, Hye Won [3 ]
机构
[1] CHA Univ, Gumi CHA Med Ctr, Dept Internal Med, Div Gastroenterol & Hepatol, Gumi 730728, South Korea
[2] Kyungpook Natl Univ, Sch Med, Dept Internal Med, Div Gastroenterol & Hepatol, Daegu 700721, South Korea
[3] Kyungpook Natl Univ, Sch Med, Dept Pathol, Daegu 700721, South Korea
关键词
Hepatocellular carcinoma; Radiofrequency ablation; Sorafenib; Down-staging; Complete remission; PHASE-II; COMBINATION; TRIAL;
D O I
10.3748/wjg.v21.i8.2568
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Sorafenib, a potent multikinase inhibitor, lead to a significant improvement in progression free survival and overall survival in patients with advanced hepatocellular carcinoma (HCC). Though sorafenib has proven its efficacy in advanced stage HCC, there are limited reports on the role of sorafenib allowing for curative treatment by down-staging. We herein report a case of advanced HCC with vascular invasion, which showed treatment response by sorafenib therapy as to allow for radiofrequency ablation as curative treatment. The patient was followed-up for 6 mo without recurrence with continued sorafenib therapy.
引用
收藏
页码:2568 / 2572
页数:5
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