Anti-Drug Antibodies Detected in the Presence of Adequate Infliximab Drug Levels In IBD Patients in Clinical Remission have Limited Clinical Significance

被引:0
|
作者
Doherty, J. [1 ]
Varley, R. [1 ]
Healy, M. [2 ]
Dunne, C. [1 ]
Mac Carthy, F. [1 ]
McKiernan, S. [1 ]
Hartery, K. [1 ]
Kevans, D. [1 ]
机构
[1] St James Hosp, Dept Gastroenterol, Dublin 8, Ireland
[2] St James Hosp, Dept Biochem, Dublin 8, Ireland
来源
关键词
D O I
10.1093/ecco-jcc/jjab076.532
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
P408
引用
收藏
页码:S415 / S416
页数:3
相关论文
共 50 条
  • [41] Clinical implications of measuring drug and anti-drug antibodies by different assays when optimizing infliximab treatment failure in Crohn's disease
    Steenholdt, C.
    Bendtzen, K.
    Brynskov, J.
    Thomsen, O. O.
    Ainsworth, M. A.
    JOURNAL OF CROHNS & COLITIS, 2014, 8 : S291 - S291
  • [42] Clinical Implications of Measuring Drug and Anti-Drug Antibodies by Different Assays When Optimizing Infliximab Treatment Failure in Crohn's Disease
    Steenholdt, Casper
    Bendtzen, Klaus
    Brynskov, Jorn
    Thomsen, Ole
    Ainsworth, Mark A.
    GASTROENTEROLOGY, 2014, 146 (05) : S240 - S240
  • [43] Rituximab in multiple sclerosis; frequency and clinical relevance of anti-drug antibodies
    Dunn, Nicky
    Juto, Alexander
    Ryner, Malin
    Manouchehrinia, Ali
    Piccoli, Luca
    Fink, Katharina
    Piehl, Fredrik
    Fogdell-Hahn, Anna
    SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 2017, 86 (04) : 342 - 343
  • [44] Presence of anti-nuclear antibodies is a risk factor for the appearance of anti-drug antibodies during infliximab or adalimumab therapy in patients with rheumatoid arthritis
    Mori, Ayano
    Saito, Toshiharu
    Takahashi, Miho
    Shibata, Miho
    Tsuji, Goh
    Hatachi, Saori
    Takahashi, Soshi
    Kumagai, Shunichi
    PLOS ONE, 2020, 15 (12):
  • [45] Rituximab in multiple sclerosis: Frequency and clinical relevance of anti-drug antibodies
    Dunn, Nicky
    Juto, Alexander
    Ryner, Malin
    Manouchehrinia, Ali
    Piccoli, Luca
    Fink, Katharina
    Piehl, Fredrik
    Fogdell-Hahn, Anna
    MULTIPLE SCLEROSIS JOURNAL, 2018, 24 (09) : 1224 - 1233
  • [46] Epitope mapping of anti-drug antibodies to a clinical candidate bispecific antibody
    Schick, Arthur J., III
    Lundin, Victor
    Low, Justin
    Peng, Kun
    Vandlen, Richard
    Wecksler, Aaron T.
    MABS, 2022, 14 (01)
  • [47] T cell response to infliximab in treated patients who develop anti-drug antibodies
    Vultaggio, A.
    Nencini, F.
    Pratesi, S.
    Zanieri, F.
    Maggi, E.
    Matucci, A.
    ALLERGY, 2016, 71 : 42 - 43
  • [48] Cell sensitization to infliximab is detectable in a proportion of treated patients without anti-drug antibodies
    Nencini, F.
    Vultaggio, A.
    Pratesi, S.
    Maggi, E.
    Matucci, A.
    ALLERGY, 2015, 70 : 404 - 404
  • [49] FINDING OF SPECIFIC ANTI-DRUG IGE AND IGG ANTIBODIES BY RIA - CLINICAL-SIGNIFICANCE AS EXEMPLIFIED BY NOMIFENSINE
    WALTI, M
    NEFTEL, K
    COHEN, M
    DEWECK, AL
    PERISIC, M
    SCHWEIZERISCHE MEDIZINISCHE WOCHENSCHRIFT, 1983, 113 (49) : 1865 - 1867
  • [50] Anti-Drug Antibodies to Certolizumab Pegol Are Assiciated with Low Drug Levels and Reduced Clinical Response at 3 Months in Patients with Inflammatory Joint Diseases
    Gehin, Johanna
    Goll, Guro Lovik
    Syversen, Siljc Watterdal
    Warren, David J.
    Sexton, Joseph
    Strand, Eldri Kvein
    Kvien, Tore
    Lie, Elisabeth
    Bolstad, Nils
    ARTHRITIS & RHEUMATOLOGY, 2018, 70