Lower- and higher-order aberrations after photorefractive keratectomy with and without compensation of pupil centroid shift: fellow eye comparison

Purpose: To study the effect of pupil centroid shift (PCS) compensation on lower- and higher-order aberrations (HOAs) after photorefractive keratectomy (PRK). Setting: Labbafinejad Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Design: Prospective intrasubject fellow eye study. Methods: One hundred twelve eyes of 56 patients with simple myopia or myopic astigmatism scheduled for PRK were enrolled. Preoperatively, the amount of PCS was measured in the horizontal and vertical directions. All eyes received wavefront-optimized treatment with static cyclotorsion compensation. PCS compensation was tumed on for the right eye of each subject (PCS-on group), and turned off for the left eye (PCS-off group). Post-operatively, refraction and corneal HOAs were compared between the study groups at 6 months. Results: Mean preoperative myopia was -3.84 diopters (D) 2.41 (SD) vs -3.75 +/- 2.27 D (P = .408), whereas mean preoperative cylinder was -1.18 D +/- 1.15 (SD) vs -1.14 +/- 1.16 D (P = .769) in the PCS-on and PCS-off groups, respectively. Mean absolute PCS values were 62.25 mu m +/- 41.82 (SD) vs 55.92 +/- 37.47 mu m (P = .45) in the horizontal direction and 65.04 +/- 47.16 mu m vs 58.40 +/- 45.44 mu m in the vertical direction (P = .29) in the PCS-on and PCS-off groups, respectively. The study groups were comparable in terms of postoperative refraction and root mean square of total corneal HOAs. Conclusions: Compensation of PCS did not affect lower- and higher-order aberrations after wavefront-optimized PRK with static cyclotorsion compensation in myopic or myopic astigmatic eyes. Copyright (C) 2020 Published by Wolters Kluwer on behalf of ASCRS and ESCRS