Chemical composition and biological activity of Tanacetum audibertii (Req.) DC. (Asteraceae), an endemic species of Sardinia Island, Italy

被引：15
|
作者：
Maxia, Andrea [1 ]
Sanna, Cinzia [1 ]
Piras, Alessandra [2 ]
Porcedda, Silvia [2 ]
Falconieri, Danilo [3 ]
Goncalves, Maria Jose [4 ,5 ]
Cavaleiro, Carlos [4 ,5 ]
Salgueiro, Ligia [4 ,5 ]
机构：
[1] Univ Cagliari, Dept Life & Environm Sci, Bot & Bot Garden Div, I-09123 Cagliari, Italy
[2] Univ Cagliari, Dipartimento Sci Chim & Geol, I-09042 Monserrato, Italy
[3] Ist Tecn Ind Statale Michele Giva, I-09100 Cagliari, Italy
[4] Univ Coimbra, Fac Farm CEF, P-3000548 Coimbra, Portugal
[5] Univ Coimbra, CNC, P-3000548 Coimbra, Portugal
来源：
INDUSTRIAL CROPS AND PRODUCTS | 2015年 / 65卷
关键词：
Tanacetum audibertii (Req.) DC; Endemic species; Supercritical carbon dioxide extracts; Hydrodistillation; Antifungal activity; ESSENTIAL OIL COMPOSITION; COLORADO POTATO BEETLES; VULGARE GROWING WILD; SESQUITERPENE LACTONES; AERIAL PARTS; PARTHENOLIDE; L; EXTRACT; TANSY; BIP;
D O I：
10.1016/j.indcrop.2014.10.039
中图分类号：
S2 [农业工程];
学科分类号：
0828 ;
摘要：
The chemical composition and antifungal activity of volatile extracts of Tanaceutum audibertii (Req.) DC., an endemic species of Sardinia and Corsica islands, were investigated. The extract and the essential oil, obtained respectively by supercritical fluid extraction with carbon dioxide (SFE) at pressures of 90 bar and temperature of 40 degrees C and by hydrodistillation (HD), were analyzed by GC/FID and GC/MS. Artemisia ketone, trans-linalyl oxide acetate and 1,8-cineole were the main components. The HD oil was evaluated against yeasts and dermatophyte strains, being more active against Cryptococtus neaformans, with MIC and MLC values of 0.64 mu L/mL. Moreover, the oil revealed an important inhibitory effect on germ tube formation in C albicans at sub-inhibitory concentrations. At the concentration of 1/16 MIC the inhibition of filamentation was more than 70% in comparison to untreated control cells. (C) 2014 Elsevier B.V. All rights reserved.
引用
收藏
页码：472 / 476
页数：5
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