CIRCULATING TUMOUR CELLS AND CIRCULATING ENDOTHELIAL CELLS AS BIOMARKERS IN ONCOLOGY

被引：4
|
作者：
Strijbos, M. H. [1 ]
机构：
[1] Ghent Univ Hosp, Dept Med Oncol, B-9000 Ghent, Belgium
来源：
ACTA CLINICA BELGICA | 2011年 / 66卷 / 05期
关键词：
circulating tumour cells; circulating endothelial cells; bionnarkers; cancer; METASTATIC COLORECTAL-CANCER; RESISTANT PROSTATE-CANCER; BREAST-CANCER; ANGIOGENESIS; CARCINOMA; SURVIVAL; CHEMOTHERAPY; BEVACIZUMAB; SUNITINIB; BENEFIT;
D O I：
10.2143/ACB.66.5.2062584
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Circulating tumour cells (CTC) and circulating endothelial cells (CEC) are considered promising biomarkers for tumour aggressiveness and vascular damage. Their number in the blood of cancer patients has already demonstrated to be of prognostic and predictive value in several studies. In addition, the molecular characterization of these cells may provide novel insight in the growth and dissemination of cancer, and help the development of new anti-neoplastic drugs. Therefore, many attempts have been made to reliably detect these extremely rare cells in the blood. In this review, we address the detection, applicability and results from clinical trials for both CTC and CEC.
引用
收藏
页码：332 / 336
页数：5
相关论文
共 50 条
  • [1] Circulating endothelial cells as biomarkers in clinical oncology
    Mancuso, Patrizia
    Bertolini, Francesco
    [J]. MICROVASCULAR RESEARCH, 2010, 79 (03) : 224 - 228
  • [2] Circulating endothelial progenitors - Cells as biomarkers
    Rosenzweig, A
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2005, 353 (10): : 1055 - 1057
  • [3] Circulating tumour cells as biomarkers in lung radiotherapy
    Haslett, K.
    [J]. RADIOTHERAPY AND ONCOLOGY, 2016, 119 : S188 - S188
  • [4] Circulating tumour cells as biomarkers in clinical trials
    de Bono, J.
    [J]. EJC SUPPLEMENTS, 2009, 7 (02): : 42 - 43
  • [5] Circulating endothelial cells in oncology: pitfalls and promises
    Strijbos, M. H.
    Gratama, J. W.
    Kraan, J.
    Lamers, C. H.
    den Bakker, M. A.
    Sleijfer, S.
    [J]. BRITISH JOURNAL OF CANCER, 2008, 98 (11) : 1731 - 1735
  • [6] Circulating endothelial cells in oncology: pitfalls and promises
    M H Strijbos
    J W Gratama
    J Kraan
    C H Lamers
    MA den Bakker
    S Sleijfer
    [J]. British Journal of Cancer, 2008, 98 : 1731 - 1735
  • [7] Circulating endothelial cells as biomarkers of prostate cancer
    Harry D Georgiou
    Benjamin Namdarian
    Niall M Corcoran
    Anthony J Costello
    Christopher M Hovens
    [J]. Nature Clinical Practice Urology, 2008, 5 : 445 - 454
  • [8] Circulating endothelial cells as biomarkers of prostate cancer
    Georgiou, Harry D.
    Namdarian, Benjamin
    Corcoran, Niall M.
    Costello, Anthony J.
    Hovens, Christopher M.
    [J]. NATURE CLINICAL PRACTICE UROLOGY, 2008, 5 (08): : 445 - 454
  • [9] Circulating endothelial cells and circulating endothelial progenitor cells in polycythemia
    Hoeg, Rasmus T.
    Jobe, Dean A.
    Asp, Krista E.
    Callister, Steven M.
    Meyer, Lori A.
    Mathiason, Michelle A.
    Cole, Craig E.
    Bottnerl, Wayne A.
    Farnen, John P.
    Go, Ronald S.
    [J]. BLOOD, 2006, 108 (11) : 311B - 311B
  • [10] Circulating tumour cells as biomarkers in early breast cancer
    Krell, Jonathan
    Stebbing, Justin
    [J]. LANCET ONCOLOGY, 2012, 13 (07): : 653 - 654
12345