Circulating endothelial cells as biomarkers of prostate cancer

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作者
Harry D Georgiou
Benjamin Namdarian
Niall M Corcoran
Anthony J Costello
Christopher M Hovens
机构
[1] Royal Melbourne Hospital.,HD Georgiou is an Advanced Medical Science Trainee in the Department of Surgery
[2] Royal Melbourne Hospital.,B Namdarian is a Urology Trainee with the Urological Society of Australia and New Zealand and is also a PhD candidate in the Department of Urology and Surgery
[3] NM Corcoran is a Urology Trainee with the Urological Society of Australia and New Zealand,and a Urology Clinical Research Fellow in the Department of Urology and Surgery
[4] Royal Melbourne Hospital.,AJ Costello is a Professorial Fellow and Head of the Department of Urology, affiliated with the Department of Surgery
[5] The Royal Melbourne Hospital,Departments of Urology and Surgery
[6] University of Melbourne.,undefined
[7] CM Hovens is Director of the Prostate Cancer Research Center,undefined
[8] Royal Melbourne Hospital,undefined
[9] University of Melbourne,undefined
[10] Australia.,undefined
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摘要
Prostate cancer has a wide spectrum of biological aggressiveness, but characterization of prostate-cancer aggressiveness at the time of diagnosis can be difficult. Tumor vascularization positively correlates with disease progression and, therefore, markers of angiogenesis could be indicators of clinical outcomes. Circulating endothelial progenitors and circulating endothelial cells play an integral part in neovascularization, and in this Review the authors discuss the potential of these cells as prognostic indicators.
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页码:445 / 454
页数:9
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