Synthesis of β- and γ-carbolines by the palladium-catalyzed iminoannulation of internal alkynes

被引：117
|
作者：
Zhang, HM [1 ]
Larock, RC [1 ]
机构：
[1] Iowa State Univ, Dept Chem, Ames, IA 50011 USA
来源：
ORGANIC LETTERS | 2001年 / 3卷 / 20期
关键词：
D O I：
10.1021/ol010124w
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
[GRAPHICS] A variety of substituted beta- and gamma -carbolines have been prepared in good to excellent yields by the annulation of internal acetylenes by the tert-butylimines of N-substituted 3-iodoindole-2-carboxaldehydes and 2-haloindole-3-carboxaldehydes, respectively, in the presence of a palladium catalyst.
引用
收藏
页码：3083 / 3086
页数：4
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