Apoptosis gene network description in the GeneNet and TRRD databases

被引:3
|
作者
Stepanenko, I [1 ]
Kolchanov, N [1 ]
机构
[1] RAS, SB, Inst Cytol & Genet, Novosibirsk 630090, Russia
关键词
gene networks; apoptosis; signal transduction;
D O I
10.1196/annals.1299.003
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The large volume of experimental data on apoptosis requires computer processing to systematize and provide an integrated "description of operation" of the gene network that regulates apoptosis in various cell types under varying effects. The database GeneNet contains the description of the apoptosis gene network: (http://wwwmgs.bionet.nsc.ru/systems/mgl/genenet), and the Transcription Regulatory Regions Database (TRRD) contains experimental data on transcription regulation of various genes, including apoptosis genes: (http://wwwmgs.bionet.nsc.ru/mgs/gnw/trrd/).
引用
收藏
页码:16 / 18
页数:3
相关论文
共 50 条
  • [1] Gene network of the arabidopsis developing shoot meristem and its description in the GeneNet computer system
    Mironova, V. V.
    Omelianchuk, N. A.
    Proceedings of the Fourth International Conference on Bioinformatics of Genome Regulation and Structure, Vol 2, 2004, : 101 - 104
  • [2] GeneNet: a gene network database and its automated visualization
    Kolpakov, FA
    Ananko, EA
    Kolesov, GB
    Kolchanov, NA
    BIOINFORMATICS, 1998, 14 (06) : 529 - 537
  • [3] Automated generation of diagrams of gene networks on the basis of their formalized description in the GeneNet database
    Anan'ko, EA
    Kolpakov, FA
    Kolesov, GB
    Kolchanov, NA
    BIOFIZIKA, 1999, 44 (04): : 628 - 631
  • [4] Databases on transcriptional regulation: TRANSFAC, TRRD and COMPEL
    Heinemeyer, T
    Wingender, E
    Reuter, I
    Hermjakob, H
    Kel, AE
    Kel, OV
    Ignatieva, EV
    Ananko, EA
    Podkolodnaya, OA
    Kolpakov, FA
    Podkolodny, NL
    Kolchanov, NA
    NUCLEIC ACIDS RESEARCH, 1998, 26 (01) : 362 - 367
  • [5] Glucocorticoid regulation mechanisms and glucocorticoid-controlled gene regulatory regions: Description in the TRRD database
    Merkulova, TI
    Merkulov, VM
    Mitina, RL
    MOLECULAR BIOLOGY, 1997, 31 (04) : 605 - 615
  • [6] Regulation of transcription of lipid metabolism genes: Description in the TRRD database
    Ignat'eva, EV
    Merkulova, TI
    Vishnevskii, OV
    Kel', AE
    MOLECULAR BIOLOGY, 1997, 31 (04) : 575 - 591
  • [7] Spatial proximity and gene function: a new dimension in prokaryotic gene association network analysis with 3D-GeneNet
    Gao, Yuan
    Ma, Bin
    Xu, Qianshuai
    Peng, Yuna
    Gong, Huimin
    Guan, Aohan
    Hua, Kexin
    Langford, Paul R.
    Jin, Hui
    Luo, Rui
    BRIEFINGS IN BIOINFORMATICS, 2024, 25 (04)
  • [8] GeneNet: a database on structure and functional organisation of gene networks
    Ananko, EA
    Podkolodny, NL
    Stepanenko, IL
    Ignatieva, EV
    Podkolodnaya, OA
    Kolchanov, NA
    NUCLEIC ACIDS RESEARCH, 2002, 30 (01) : 398 - 401
  • [9] TRRD and COMPEL databases on transcription linked to TRANSFACAS as tools for analysis and recognition of regulatory sequences
    Kel, AE
    Kel, OV
    Vishnevsky, OV
    Ponomarenko, MP
    Ischenko, IV
    Karas, H
    Kolchanov, NA
    Sklenar, H
    Wingender, E
    BIOINFORMATICS, 1997, 1278 : 99 - 105
  • [10] An integration of the descriptions of gene networks and their models presented in sigmoid (cellerator) and genenet
    Podkolodny, N. L.
    Podkolodnaya, N. N.
    Miginsky, D. S.
    Poplavsky, A. S.
    Likhoshvai, V. A.
    Compani, B.
    Mjolsness, E.
    PROCEEDINGS OF THE FIFTH INTERNATIONAL CONFERENCE ON BIOINFORMATICS OF GENOME REGULATION AND STRUCTURE, VOL 3, 2006, : 86 - +