Reduced default mode network connectivity in schizophrenia patients

被引：32
|
作者：
Pankow, Anne [1 ]
Deserno, Lorenz [1 ,2 ,3 ]
Walter, Martin [3 ,4 ,6 ]
Fydrich, Thomas [5 ]
Bermpohl, Felix [1 ]
Schlagenhauf, Florian [1 ,2 ]
Heinz, Andreas [1 ]
机构：
[1] Univ Med Berlin, Dept Psychiat & Psychotherapy, Charite, D-10117 Berlin, Germany
[2] Max Planck Inst Human Cognit & Brain Sci, Max Planck Fellow Grp Cognit & Affect Control Beh, Leipzig, Germany
[3] Univ Magdeburg, Dept Neurol, D-39106 Magdeburg, Germany
[4] Univ Magdeburg, Dept Psychiat, D-39106 Magdeburg, Germany
[5] Humboldt Univ, Dept Psychol, Berlin, Germany
[6] Leibniz Inst Neurobioloy, Magdeburg, Germany
来源：
SCHIZOPHRENIA RESEARCH | 2015年 / 165卷 / 01期
关键词：
Schizophrenia; Default mode network; Functional imaging; FUNCTIONAL CONNECTIVITY; BRAIN; METAANALYSIS; ACTIVATION;
D O I：
10.1016/j.schres.2015.03.027
中图分类号：
R749 [精神病学];
学科分类号：
100205 ;
摘要：
In the present study, we explored possible alterations in the default mode network (DMN) and its functional connectivity in 41 schizophrenia patients and 42 age-matched healthy controls. Schizophrenia patients displayed reduced activation in the ventromedial prefrontal cortex, left superior temporal gyrus including auditory cortex and temporal pole. Psychophysiological interaction analysis revealed reduced connectivity between left superior temporal gyrus including auditory cortex and the left temporal pole in schizophrenia patients compared to healthy subjects. (C) 2015 Elsevier B.V. All rights reserved.
引用
下载
收藏
页码：90 / 93
页数：4
相关论文
共 50 条
  • [41] Altered Default Mode Network Connectivity in Patients with Late Life Depression
    Lavretsky, Helen
    Yang, Hongue
    Leaver, Amber
    Narr, Katherine
    NEUROPSYCHOPHARMACOLOGY, 2014, 39 : S181 - S182
  • [42] Acupuncture Modulates the Functional Connectivity of the Default Mode Network in Stroke Patients
    Zhang, Yong
    Li, Kuangshi
    Ren, Yi
    Cui, Fangyuan
    Xie, Zijing
    Shin, Jae-Young
    Tan, Zhongjian
    Tang, Lixin
    Bai, Lijun
    Zou, Yihuai
    EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2014, 2014
  • [43] Default Mode Network Activity and Connectivity in Psychopathology
    Whitfield-Gabrieli, Susan
    Ford, Judith M.
    ANNUAL REVIEW OF CLINICAL PSYCHOLOGY, VOL 8, 2012, 8 : 49 - +
  • [44] Default mode network connectivity in patients with idiopathic normal pressure hydrocephalus
    Khoo, Hui Ming
    Kishima, Haruhiko
    Tani, Naoki
    Oshino, Satoru
    Maruo, Tomoyuki
    Hosomi, Koichi
    Yanagisawa, Takufumi
    Kazui, Hiroaki
    Watanabe, Yoshiyuki
    Shimokawa, Toshio
    Aso, Toshihiko
    Kawaguchi, Atsushi
    Yamashita, Fumio
    Saitoh, Youichi
    Yoshimine, Toshiki
    JOURNAL OF NEUROSURGERY, 2016, 124 (02) : 350 - 358
  • [45] Default Mode Network Connectivity in Pediatric PTSD
    Patriat, Remi
    Herringa, Ryan
    BIOLOGICAL PSYCHIATRY, 2014, 75 (09) : 356S - 356S
  • [46] Greater Perceived Stress is Associated With Reduced Default Mode to Salience Network Connectivity in Adolescents
    Del Giacco, Amanda
    Morales, Angelica
    Jones, Scott
    Nagel, Bonnie
    BIOLOGICAL PSYCHIATRY, 2023, 93 (09) : S298 - S298
  • [47] Reduced Default Mode Connectivity in Adolescents With Conduct Disorder
    Broulidakis, M. John
    Fairchild, Graeme
    Sully, Kate
    Blumensath, Thomas
    Darekar, Angela
    Sonuga-Barke, Edmund J. S.
    JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY, 2016, 55 (09): : 800 - 808
  • [48] Reduced default mode network connectivity in treatment-resistant idiopathic generalized epilepsy
    Kay, Benjamin P.
    DiFrancesco, Mark W.
    Privitera, Michael D.
    Gotman, Jean
    Holland, Scott K.
    Szaflarski, Jerzy P.
    EPILEPSIA, 2013, 54 (03) : 461 - 470
  • [49] Reduced default mode network effective connectivity in healthy aging is modulated by years of education
    Stoffel, Tibor
    Vaque-Alcazar, Lidia
    Bartres-Faz, David
    Pero-Cebollero, Maribel
    Canete-Masse, Cristina
    Guardia-Olmos, Joan
    NEUROIMAGE, 2024, 288
  • [50] Treatment with Olanzapine is Associated with Modulation of the Default Mode Network in Patients with Schizophrenia
    Fabio Sambataro
    Giuseppe Blasi
    Leonardo Fazio
    Grazia Caforio
    Paolo Taurisano
    Raffaella Romano
    Annabella Di Giorgio
    Barbara Gelao
    Luciana Lo Bianco
    Apostolos Papazacharias
    Teresa Popolizio
    Marcello Nardini
    Alessandro Bertolino
    Neuropsychopharmacology, 2010, 35 : 904 - 912
12345