Detoxification of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) by glucuronidation

被引：0
|
作者：
Murphy, SE [1 ]
Spina, DA [1 ]
Pullo, DA [1 ]
机构：
[1] AMER HLTH FDN,VALHALLA,NY 10595
来源：
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 1996年 / 212卷
关键词：
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
引用
收藏
页码：62 / TOXI
页数：1
相关论文
共 50 条
  • [21] Recent studies on mechanisms of bioactivation and detoxification of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), a tobacco-specific lung carcinogen
    Hecht, SS
    CRITICAL REVIEWS IN TOXICOLOGY, 1996, 26 (02) : 163 - 181
  • [22] The tobacco specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) induces apoptosis of endothelial cells
    Tithof, PK
    Weddle, D
    Schuller, HM
    Barnhill, M
    FASEB JOURNAL, 2000, 14 (04): : A455 - A455
  • [23] DETERMINANTS OF A GENOTOXIC EFFECT OF 4-(METHYLNITROSAMINO)-1-(3-PYRIDYL)-1-BUTANONE (NNK) IN HUMAN-DIPLOID FIBROBLASTS
    POHLMANN, C
    KOOPS, F
    BERG, J
    HOLZ, O
    EHLERT, U
    RUDIGER, HW
    CLINICAL INVESTIGATOR, 1992, 70 (3-4): : 295 - 298
  • [24] IDENTIFICATION OF 4-(METHYLNITROSAMINO)-1-[3-(6-HYDROXYPYRIDYL)]-1-BUTANONE AS A URINARY METABOLITE OF 4-(METHYLNITROSAMINO)-1-(3-PYRIDYL)-1-BUTANONE IN RODENTS
    DESAI, D
    KAGAN, SS
    AMIN, S
    CARMELLA, SG
    HECHT, SS
    CHEMICAL RESEARCH IN TOXICOLOGY, 1993, 6 (06) : 794 - 799
  • [25] Mutations induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in the lacZ and cII genes of MutaTM Mouse
    Hashimoto, K
    Ohsawa, K
    Kimura, M
    MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS, 2004, 560 (02) : 119 - 131
  • [26] SYNTHESIS OF [4-(H-2)2]-4-(METHYLNITROSAMINO)-1-(3'-PYRIDYL)-1-BUTANONE, (4R)-4-(METHYLNITROSAMINO)-1-(3'-PYRIDYL)-1-BUTANONE AND (4S)-4-(METHYLNITROSAMINO)-1-(3'-PYRIDYL)-1-BUTANONE, C-4 DEUTERIATED ISOTOPOMERS OF THE PROCARCINOGEN NNK
    PATHAK, T
    THOMAS, NF
    AKHTAR, M
    GANI, D
    TETRAHEDRON, 1990, 46 (05) : 1733 - 1744
  • [27] Absence of metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) by flavin-containing monooxygenase (FMO)
    Lamoureux, J
    Castonguay, A
    CARCINOGENESIS, 1997, 18 (10) : 1979 - 1984
  • [28] Epigenetic changes in cells and animals treated with tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)
    Kotandeniya, Delshanee
    Kassie, Fekadu
    Song, Jungmin
    Qian, Xuemin
    Tretyakova, Natalia
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2013, 246
  • [29] Carbonyl reduction of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) by cytosolic enzymes in human liver and lung
    Maser, E
    Stinner, B
    Atalla, A
    CANCER LETTERS, 2000, 148 (02) : 135 - 144
  • [30] Bayesian derivation of an oral cancer slope factor distribution for 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)
    Naufal, Z.
    Kathman, S.
    Wilson, C.
    REGULATORY TOXICOLOGY AND PHARMACOLOGY, 2009, 55 (01) : 69 - 75
12345