Synthesis and properties of composite biomaterials based on hydroxyapatite and poly(L-lactide)

被引：10
|
作者：
Zhou Zhihua [1 ]
Ruan Jianming [2 ]
Zhou Zhongcheng [2 ]
Zou Jianpeng [2 ]
机构：
[1] Hunan Univ Sci & Technol, Coll Chem & Chem Engn, Xiangtan, Peoples R China
[2] Cent S Univ, State Key Lab Powder Met, Changsha 410083, Peoples R China
来源：
POLYMER-PLASTICS TECHNOLOGY AND ENGINEERING | 2008年 / 47卷 / 05期
基金：
中国国家自然科学基金;
关键词：
biocompatibility; composite; hydroxyapatite; poly(L-lactide); properties; synthesis;
D O I：
10.1080/03602550801952300
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
Composite biomaterial composed of poly(L-lactide) (PLLA) and hydroxyapatite (HA) was obtained by using the combination of solvent evaporation technique and hot pressing. HA particles in the PLLA matrix were homogeneously dispersed. A typical morphology of brittle failure with a smooth fracture surface was observed. The addition of HA particles changed significantly the appearance of the impact fracture surface to a pattern of multiple cracks. With the increasing of the amount of the HA, the bending strength of composite decreases while the bending modulus increases. The PLLA/HA composite exhibits improved cell compatibility due to the good biocompatibility of the HA particles.
引用
收藏
页码：496 / 501
页数：6
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