Modular Synthase-Encoding Gene Involved in α-Olefin Biosynthesis in Synechococcus sp Strain PCC 7002

被引:114
|
作者
Mendez-Perez, Daniel [1 ]
Begemann, Matthew B. [1 ,2 ]
Pfleger, Brian F. [1 ,2 ,3 ]
机构
[1] Univ Wisconsin, Dept Chem & Biol Engn, Madison, WI 53706 USA
[2] Univ Wisconsin, Microbiol Doctoral Training Program, Madison, WI 53706 USA
[3] Univ Wisconsin, Great Lakes Bioenergy Res Ctr, Madison, WI 53706 USA
关键词
BLUE-GREEN-ALGAE; FATTY-ACIDS; GEOCHEMICAL SIGNIFICANCE; POLYKETIDE SYNTHASE; ENZYMATIC DOMAINS; ESCHERICHIA-COLI; HYDROCARBONS; CYANOBACTERIA; ORGANIZATION; SPECIFICITY;
D O I
10.1128/AEM.00467-11
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
gene involved in the production of medium-chain alpha-olefins was identified in the cyanobacterium Synechococcus sp. strain PCC 7002. The gene encodes a large multidomain protein with homology to type I polyketide synthases, suggesting a route for hydrocarbon biosynthesis from fatty acids via an elongation decarboxylation mechanism.
引用
收藏
页码:4264 / 4267
页数:4
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