Rare and transient anti-D antibody response in D- liver transplant recipients transfused with D+ red blood cells

被引：9
|
作者：
des Roziers, N. Burin [1 ]
Ibanez, C. [1 ]
Samuel, D. [2 ]
Francoz, C. [3 ]
Idri, S. [1 ]
Francois, A. [1 ]
Mortelecque, R. [1 ]
Bierling, P. [1 ,4 ]
Pirenne, F. [1 ,4 ]
机构：
[1] Etab Francais Sang Ile France, Villejuif, France
[2] Hop Paul Brousse, Ctr Hepatobiliaire, Villejuif, France
[3] Hop Beaujon, Serv Hepatol & Reanimat Hepatodigest, Clichy, France
[4] Inst Mondor, Lab Excellence, Inserm,Equipe Transfus & Malad Globule Rouge 2, U955,GRex, Creteil, France
来源：
VOX SANGUINIS | 2016年 / 111卷 / 01期
关键词：
antibody formation; blood transfusion; haemolysis; immunosuppression; liver transplantation; Rh-Hr blood group system; ALLOIMMUNIZATION; HEART;
D O I：
10.1111/vox.12392
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
A retrospective analysis was conducted on 20 D- liver transplant (LT) recipients transfused with D+ RBCs perioperatively and screened for RBC antibodies between 2 and 6 months later. None developed anti-D detectable by the indirect antiglobulin test. Two patients produced weak anti-D that reacted only with papain-treated RBCs at 10 and 11 days without any sign of immune haemolysis. Antibodies became quickly undetectable. These data suggest an unusual pattern of alloimmunization in LT recipients with rapid, weak and transient antibody response and support the safety of transfusing D+ RBCs in most of D- patients during LT surgery.
引用
收藏
页码：107 / 110
页数：4
相关论文
共 50 条
  • [1] Detection of anti-D in D- recipients transfused with D+ red blood cells
    Yazer, Mark H.
    Triulzi, Darrell J.
    TRANSFUSION, 2007, 47 (12) : 2197 - 2201
  • [2] Incidence of anti-D alloimmunization in D- recipients transfused with D+ RBCs
    Yazer, M. H.
    Triulzi, D. J.
    TRANSFUSION, 2007, 47 (03) : 10A - 10A
  • [3] Predisposing factors for anti-D immune response in D- patients with chronic liver disease transfused with D+ platelet concentrates
    des Roziers, Nicolas Burin
    Chadebech, Philippe
    Malard, Lucile
    Vingert, Benoit
    Gallon, Philippe
    Samuel, Didier
    Djoudi, Rachid
    Fillet, Anne-Marie
    Pirenne, France
    TRANSFUSION, 2019, 59 (04) : 1353 - 1358
  • [4] Evaluation of anti-D alloimmunization in D-recipients of D+ RBCs
    Lorenzi, M.
    Venturino, E.
    Bisignano, L.
    Bordiga, A. M.
    TRANSFUSION, 2008, 48 (02) : 77A - 77A
  • [5] Probability of anti-D development in D- patients receiving D+ RBCs
    Frohn, C
    Dümbgen, L
    Brand, JM
    Görg, S
    Luhm, J
    Kirchner, H
    TRANSFUSION, 2003, 43 (07) : 893 - 898
  • [6] Risk of Anti-D in Patients with Partial D, DAU0, or Conventional D Transfused with D+ Minority Donors
    Takasaki, Kaoru
    Uter, Stacey
    Vege, Sunitha
    Friedman, David F.
    Westhoff, Connie M.
    Chou, Stella T.
    TRANSFUSION, 2022, 62 : 19A - 20A
  • [7] Critical review of transfusion of D+ red blood cells to D- patients.
    Riccardi, D
    Manera, MC
    Pizzi, MN
    Raspollini, E
    Ratto, A
    Rebulla, P
    TRANSFUSION, 2002, 42 (09) : 100S - 100S
  • [8] Prospective evaluation of a transfusion policy of D+ red blood cells into D- patients
    Gonzalez-Porras, Jose R.
    Graciani, Ignacio E.
    Perez-Simon, Jose A.
    Martin-Sanchez, Jesus
    Encinas, Cristina
    Conde, Maria P.
    Nieto, Maria J.
    Corral, Mercedes
    TRANSFUSION, 2008, 48 (07) : 1318 - 1324
  • [9] Anti-D immunization by DEL red blood cells
    Wagner, T
    Körmöczi, GF
    Buchta, C
    Vadon, M
    Lanzer, G
    Mayr, WR
    Legler, TJ
    TRANSFUSION, 2005, 45 (04) : 520 - 526
  • [10] Anti-D alloimmunization after transfusion of D plus red blood cells
    Cid, Joan
    Ramiro, Laia
    TRANSFUSION, 2009, 49 (01) : 186 - 186
12345