Preparation of 'carba' dipeptides bearing a basic side-chain at the C-terminus:: synthesis of enantiopure Boc-D-Phe-Ψ[CH2CH2]-L-Arg(NO2)-OH and Boc-D-Phe-Ψ[CH2CH2]-D-Arg(NO2)-OH

被引：10

作者：

Kende, AS

Dong, HQ

Mazur, AW

Ebetino, FH

机构：

[1] Univ Rochester, Dept Chem, Rochester, NY 14627 USA

[2] Procter & Gamble Pharmaceut, Hlth Care Res Ctr, Mason, OH 45040 USA

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 35期

关键词：

'carba' dipeptide; arginine; guanidination;

D O I：

10.1016/S0040-4039(01)01183-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new approach to synthesize 'carba' Psi [CH2CH2] dipeptides. e.g. Boc-D-Phe-Psi [CH2CH2]-L-Arg(NO2)-OH and Boc-D-Phe-Psi [CH2CH2]-D-Arg(NO2)-OH, is described. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：6015 / 6018

页数：4

共 27 条

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