Preparation of 'carba' dipeptides bearing a basic side-chain at the C-terminus:: synthesis of enantiopure Boc-D-Phe-Ψ[CH2CH2]-L-Arg(NO2)-OH and Boc-D-Phe-Ψ[CH2CH2]-D-Arg(NO2)-OH

被引：10
|
作者：
Kende, AS
Dong, HQ
Mazur, AW
Ebetino, FH
机构：
[1] Univ Rochester, Dept Chem, Rochester, NY 14627 USA
[2] Procter & Gamble Pharmaceut, Hlth Care Res Ctr, Mason, OH 45040 USA
来源：
TETRAHEDRON LETTERS | 2001年 / 42卷 / 35期
关键词：
'carba' dipeptide; arginine; guanidination;
D O I：
10.1016/S0040-4039(01)01183-2
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A new approach to synthesize 'carba' Psi [CH2CH2] dipeptides. e.g. Boc-D-Phe-Psi [CH2CH2]-L-Arg(NO2)-OH and Boc-D-Phe-Psi [CH2CH2]-D-Arg(NO2)-OH, is described. (C) 2001 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：6015 / 6018
页数：4
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