Disruption of the MDM2-p53 interaction synergizes with MEK inhibition to induce cell death and promote tumor regression in p53 wild-type, Ras or Raf-mutant tumor models

被引：0

作者：

Meaux, Isabelle ^{[1
]}

Nicolas, Jean-Paul ^{[1
]}

Rowley, Steve ^{[2
]}

Sidhu, Sukhvinder ^{[1
]}

Herve, Francoise ^{[1
]}

Dassencourt, Laurent ^{[1
]}

Windenberger, Fanny ^{[1
]}

Gorge-Bernat, Dimitri ^{[1
]}

Pannier, Pascal ^{[1
]}

Bergstrom, Donald ^{[2
]}

Debussche, Laurent ^{[1
]}

Watters, James ^{[2
]}

机构：

[1] Sanofi Oncol, Vitry Sur Seine, France

[2] Sanofi Oncol, Cambridge, MA USA

来源：

CANCER RESEARCH | 2014年 / 74卷 / 19期

关键词：

D O I：

10.1158/1538-7445.AM2014-805

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

805

引用

页数：2

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