Disruption of the MDM2-p53 interaction synergizes with MEK inhibition to induce cell death and promote tumor regression in p53 wild-type, Ras or Raf-mutant tumor models

被引:0
|
作者
Meaux, Isabelle [1 ]
Nicolas, Jean-Paul [1 ]
Rowley, Steve [2 ]
Sidhu, Sukhvinder [1 ]
Herve, Francoise [1 ]
Dassencourt, Laurent [1 ]
Windenberger, Fanny [1 ]
Gorge-Bernat, Dimitri [1 ]
Pannier, Pascal [1 ]
Bergstrom, Donald [2 ]
Debussche, Laurent [1 ]
Watters, James [2 ]
机构
[1] Sanofi Oncol, Vitry Sur Seine, France
[2] Sanofi Oncol, Cambridge, MA USA
关键词
D O I
10.1158/1538-7445.AM2014-805
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
805
引用
收藏
页数:2
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