Characterization of a novel HLA-B*40 allele, HLA-B*40:186:02, by cloning and sequencing

被引：6
|
作者：
Wang, W. Y. [1 ]
Zhang, W. [2 ,3 ]
Cai, J. H. [1 ,4 ]
Zhu, F. M. [2 ,3 ]
Tian, W. [1 ]
机构：
[1] Cent S Univ, Dept Immunol, Coll Basic Med Sci, Immunogenet Res Grp, Changsha, Hunan, Peoples R China
[2] Blood Ctr Zhejiang Prov, HLA Typing Lab, Hangzhou, Zhejiang, Peoples R China
[3] Minist Hlth, Key Lab Blood Safety Res, Hangzhou, Zhejiang, Peoples R China
[4] Brains Hosp Hunan Prov, Changsha, Hunan, Peoples R China
来源：
INTERNATIONAL JOURNAL OF IMMUNOGENETICS | 2016年 / 43卷 / 04期
关键词：
IDENTIFICATION; POPULATION;
D O I：
10.1111/iji.12273
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
A novel HLA-B*40 variant, HLA-B*40:186:02, has been identified by cloning and sequencing in a southern Chinese Han population. Aligned with HLA-B*40:01:01, HLA-B*40:186:02 has a nonsynonymous cytosine mutation at nucleotide position 165 in exon 2, leading to amino acid change from glycine to arginine at codon 56. It differs from HLA-B*40:186:01 by a synonymous change (adenine to cytosine) at position 165 in exon 2.
引用
收藏
页码：240 / 241
页数：2
相关论文
共 50 条
  • [21] Characterization of the novel HLA-B*40:01:02:48 allele by next-generation sequencing
    Chen, Nanying
    Dong, Lina
    Zhao, Shuoxian
    Zhang, Wei
    Zhu, Faming
    HLA, 2024, 103 (01)
  • [22] Characterization of the novel HLA-B*40:495 and HLA-B*40:512 alleles by next-generation sequencing
    He, Yizhen
    Chen, Nanying
    Dong, Lina
    Zhang, Wei
    Zhu, Faming
    HLA, 2023, 102 (01) : 81 - 83
  • [23] Characterization of the novel HLA-B*40:01:31 allele
    Zheng, J. W.
    Sun, Y.
    Xie, J. H.
    Xiang, D.
    HLA, 2018, 91 (03) : 200 - 201
  • [24] The Full-Length Genomic Sequence of the HLA-B*40:186:02 Allele
    Tian, Wei
    Li, Lixin
    HLA, 2024, 104 (06)
  • [25] Characterization of a novel HLA allele, HLA-B*40:128, in a Chinese individual
    Zhu, F-M.
    Zhang, W.
    Wang, W.
    Lv, H-J.
    Yan, L-X.
    TISSUE ANTIGENS, 2011, 77 (03): : 260 - U2
  • [26] Characterization of the novel HLA-B*52:02:02 allele
    Zheng, Jie W.
    Xie, Jun Hua
    Sun, Ying
    Xiang, Dong
    HLA, 2021, 98 (05) : 476 - 477
  • [27] Characterization of a novel HLA-B allele (HLA-B*18:108) by intron-exon sequencing of the HLA-B locus
    Curcio, M.
    Sciarrino, R.
    Biagini, C.
    Marchetti, L.
    Gobbo, F.
    Scatena, A.
    Presciuttini, S.
    TISSUE ANTIGENS, 2015, 86 (03): : 209 - 210
  • [28] Characterization of the novel HLA-B*40:450 allele by next-generation sequencing
    Genebrier, Steve
    Elsermans, Vincent
    Texeraud, Emeric
    Bertrand, Gerald
    Renac, Virginie
    HLA, 2021, 98 (02) : 160 - 162
  • [29] Characterization of the novel HLA-B*40:02:35 allele by two next-generation sequencing methods
    Walencik, Alexandre
    Calvo De Olmos, Orane
    Bonneville, Francoise
    Blanchet, Gaelle
    Cesbron-Gautier, Anne
    HLA, 2022, 99 (03) : 209 - 210
  • [30] Characterization of the novel HLA-B*40:366 allele by sequencing-based typing
    Zhang, L. -Q.
    Xiao, Y.
    Zhou, X.
    Cai, J. -P.
    HLA, 2018, 92 (02) : 102 - 103
12345