Management of coagulopathy and hemorrhage during orthotopic liver transplantation

被引：0
|
作者：
Roullet, Stephanie [1 ]
Stecken, Laurent [1 ]
Ottolenghi, Laetitia [1 ]
Roche-Barreau, Marie [1 ]
Quinart, Alice [1 ]
机构：
[1] Ctr Hosp Pellegrin Tripode, Serv Anesthesie Reanimat 1, Unite Transplantat Hepat & Renale, F-33076 Bordeaux, France
来源：
SANG THROMBOSE VAISSEAUX | 2011年 / 23卷
关键词：
coagulation; transfusion; liver transplantation; CONVENTIONAL COAGULATION TESTS; INTRAOPERATIVE BLOOD SALVAGE; PRODUCT REQUIREMENTS; TRANSFUSION; DISEASE; HEMOSTASIS; FIBRINOGEN; DISORDERS; PLATELETS; CELLS;
D O I：
10.1684/stv.2011.0623
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Management of coagulopathy and hemorrhage during orthotopic liver transplantation Orthotopic liver transplantation concerns patients with acute or chronic liver failure. Liver disease is responsible of haemostatic disorders: primary and secondary haemostasis and fibrinolysis. This results in a rebalanced haemostasis in cirrhotic patients. During the different steps of transplantation procedure coagulation defects appear, associated with bleeding, hardly predictable. Prophylactic correction of biologic disturbances can no more be recommended if no bleeding is associated. Per operative blood salvage and retransfusion is safe. Transfusion of homologous blood products has negative side effects. The role of point-of-care coagulation devices has to be determined. Further studies are warranted to elaborate recommendations for the management of coagulopathy and hemorrhage during liver transplantation.
引用
收藏
页码：29 / 34
页数：6
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