Application of genome-editing technology in crop improvement

被引:6
|
作者
Ni, Zhe [1 ,2 ]
Han, Qian [1 ,2 ]
He, Yong-Qiang [1 ,2 ]
Huang, Sheng [1 ,2 ]
机构
[1] Guangxi Univ, Coll Life Sci & Technol, Nanning, Guangxi, Peoples R China
[2] State Key Lab Conservat & Utilizat Subtrop Agrobi, Nanning, Guangxi, Peoples R China
基金
中国国家自然科学基金;
关键词
CRISPR; Cas9; genetic breeding; genome editing; transcription activator-like effector nuclease; zinc finger nuclease; DNA-BINDING SPECIFICITY; TAL EFFECTOR NUCLEASES; DOUBLE-STRAND BREAKS; HOMOLOGOUS RECOMBINATION; GUIDE RNA; TARGETED MUTAGENESIS; TRANSCRIPTIONAL ACTIVATION; PLANT GENOMES; WEB TOOL; GENE;
D O I
10.1094/CCHEM-05-17-0101-FI
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
Background and objectivesIncrease in the world population is usually followed by a growing demand for food and increasingly higher requirements for the quality of food. The existing crops may require immediate improvement and optimization in order to adjust to market demands and the deteriorating environment. FindingsGenome-editing technology, a relatively advanced technology method that appeared in recent years, can accurately edit (i.e., insert, delete, or replace) genes and directionally modify crops by changing the plant's heredity and performance. ConclusionsCurrently, some of the modern genome-editing approaches have been applied rather widely in crop breeding: for example, zinc finger nuclease, transcription activator-like effector nuclease, and clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein. Significance and noveltyWhile reviewing the principles of the above genome-editing technologies and their research progress in crop improvement, this study will discuss the commercial application and future development of these technologies.
引用
收藏
页码:35 / 48
页数:14
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