PD-1 Axis Inhibitors in EGFR- and ALK-Driven Lung Cancer: Lost Cause?

被引:29
|
作者
Gettinger, Scott [1 ]
Politi, Katerina [1 ]
机构
[1] Yale Univ, Sch Med, Yale Canc Ctr, New Haven, CT USA
关键词
IMMUNE ESCAPE; EXPRESSION; ACTIVATION; MUTATIONS;
D O I
10.1158/1078-0432.CCR-16-1401
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Programmed death axis 1 (PD-1) inhibitors have ushered in a new error of cancer immunotherapeutics for advanced smoking-associated non-small cell lung cancer. Their role in treating EGFR-mutant and ALK-rearranged lung cancer has yet to be determined. (C) 2016 AACR.
引用
收藏
页码:4539 / 4541
页数:3
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